English

Exact Designs for OofA Experiments Under a Transition-Effect Model

Methodology 2024-11-07 v1

Abstract

In the chemical, pharmaceutical, and food industries, sometimes the order of adding a set of components has an impact on the final product. These are instances of the order-of-addition (OofA) problem, which aims to find the optimal sequence of the components. Extensive research on this topic has been conducted, but almost all designs are found by optimizing the DD-optimality criterion. However, when prediction of the response is important, there is still a need for II-optimal designs. A new model for OofA experiments is presented that uses transition effects to model the effect of order on the response, and the model is extended to cover cases where block-wise constraints are placed on the order of addition. Several algorithms are used to find both DD- and II-efficient designs under this new model for many run sizes and for large numbers of components. Finally, two examples are shown to illustrate the effectiveness of the proposed designs and model at identifying the optimal order of addition, even under block-wise constraints.

Keywords

Cite

@article{arxiv.2411.03504,
  title  = {Exact Designs for OofA Experiments Under a Transition-Effect Model},
  author = {Jiayi Zheng and Nicholas Rios},
  journal= {arXiv preprint arXiv:2411.03504},
  year   = {2024}
}

Comments

This article was previously submitted as 5973994 and marked as a duplicate of 5973519, which led to both being rejected. After discussing with my advisor, we decided to submit only to arXiv to avoid further inconvenience. Thank you for your time and understanding

R2 v1 2026-06-28T19:49:32.715Z