Effect of Electro-Diffusion Current Flow on Electrostatic Screening in Aqueous Pores
Biological Physics
2009-11-13 v1 Instrumentation and Detectors
Abstract
A numerical study within the framework of the Poisson-Nernst-Planck equations is conducted to investigate electrostatic screening of charged bio-molecules within synthetic pores having diameters of at least 10 Debye lengths. We show that with external biases, the bio-molecule charge is only partially screened due to the presence of electrodiffusion current flow. This is considerably different from the equilibrium Debye-Huckel screening behavior and will result in long-range electrostatic interactions. The potential application to direct bio-molecule charge sensing is also discussed.
Cite
@article{arxiv.0712.2478,
title = {Effect of Electro-Diffusion Current Flow on Electrostatic Screening in Aqueous Pores},
author = {Yang Liu and Jon Sauer and Robert Dutton},
journal= {arXiv preprint arXiv:0712.2478},
year = {2009}
}