Diamond nano-pillar arrays for quantum microscopy of neuronal signals
Abstract
Modern neuroscience is currently limited in its capacity to perform long term, wide-field measurements of neuron electromagnetics with nanoscale resolution. Quantum microscopy using the nitrogen vacancy centre (NV) can provide a potential solution to this problem with electric and magnetic field sensing at nano-scale resolution and good biocompatibility. However, the performance of existing NV sensing technology does not allow for studies of small mammalian neurons yet. In this paper, we propose a solution to this problem by engineering NV quantum sensors in diamond nanopillar arrays. The pillars improve light collection efficiency by guiding excitation/emission light, which improves sensitivity. More importantly, they also improve the size of the signal at the NV by removing screening charges as well as coordinating the neuron growth to the tips of the pillars where the NV is located. Here, we provide a growth study to demonstrate coordinated neuron growth as well as the first simulation of nano-scopic neuron electric and magnetic fields to assess the enhancement provided by the nanopillar geometry.
Keywords
Cite
@article{arxiv.1901.08743,
title = {Diamond nano-pillar arrays for quantum microscopy of neuronal signals},
author = {Liam Hanlon and Vini Gautam and James D. A. Wood and Prithvi Reddy and Michael S. J. Barson and Marika Niihori and Alexander R. J. Silalahi and Ben Corry and Joerg Wrachtrup and Matthew J. Sellars and Vincent R. Daria and Patrick Maletinsky and Gregory J. Stuart and Marcus W. Doherty},
journal= {arXiv preprint arXiv:1901.08743},
year = {2019}
}
Comments
18 pages including supplementary and references, 12 figures