English

Biophysical Sequence Analysis of Functional Differences of Piezo1 and Piezo2

Other Quantitative Biology 2023-01-02 v1

Abstract

Because of their large size and widespread mechanosensitive interactions the only recently discovered titled transmembrane proteins have attracted much attention. Here we present and discuss their hydropathic profiles using a new method of sequence analysis. We find large-scale similarities and differences not obtainable by conventional sequence or structural studies. These differences support the evolution-towards-criticality conjecture popular among physicists.

Keywords

Cite

@article{arxiv.2212.14754,
  title  = {Biophysical Sequence Analysis of Functional Differences of Piezo1 and Piezo2},
  author = {J. C. Phillips},
  journal= {arXiv preprint arXiv:2212.14754},
  year   = {2023}
}

Comments

10 page, two figures