Base Pair Openings and Temperature Dependence of DNA Flexibility
Statistical Mechanics
2012-02-20 v2 Soft Condensed Matter
Biological Physics
Biomolecules
Abstract
The relationship of base pair openings to DNA flexibility is examined. Published experimental data on the temperature dependence of the persistence length by two different groups are well described in terms of an inhomogeneous Kratky-Porot model with soft and hard joints, corresponding to open and closed base pairs, and sequence-dependent statistical information about the state of each pair provided by a Peyrard-Bishop-Dauxois (PBD) model calculation with no freely adjustable parameters.
Keywords
Cite
@article{arxiv.1201.6561,
title = {Base Pair Openings and Temperature Dependence of DNA Flexibility},
author = {Nikos Theodorakopoulos and Michel Peyrard},
journal= {arXiv preprint arXiv:1201.6561},
year = {2012}
}