Axial localization of luminophores by partial coherence interferometry
Biological Physics
2016-08-16 v1 Instrumentation and Detectors
Abstract
We propose a solution for increasing the axial resolution of confocal microscopes. In the experimental set-up described in this paper an interference phenomenon between two counterpropagating beams is used to determine the axial position of a luminophore. The optical path difference between the two waves, which is related to the position of the luminophore, is recovered thanks to a second interferometer by using partial coherence interferometry demodulation technique. The proposed solution can find applications in biology for localizing with nanometric resolution a small number of tagged species.
Keywords
Cite
@article{arxiv.physics/0606080,
title = {Axial localization of luminophores by partial coherence interferometry},
author = {Nicolas Sandeau and Hervé Rigneault and Pierre François Lenne and Hugues Giovannini and the Mosaic Collaboration},
journal= {arXiv preprint arXiv:physics/0606080},
year = {2016}
}