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Wide-field fluorescence microscopy, while much faster than confocal microscopy, suffers from a lack of optical sectioning and poor axial resolution. 3D structured illumination microscopy (SIM) has been demonstrated to provide optical…

Interferometry provides one of the possible routes to ultra-high angular resolution for X-ray and gamma-ray astronomy. Sub-micro-arc-second angular resolution, necessary to achieve objectives such as imaging the regions around the event…

Instrumentation and Methods for Astrophysics · Physics 2009-07-31 G. K. Skinner , J. F. Krizmanic

A recently introduced two-channel confocal microscope with correlated detection promises up to 50% improvement in transverse spatial resolution [Simon, Sergienko, Optics Express {\bf 18}, 9765 (2010)] via the use of photon correlations.…

Quantum Physics · Physics 2015-05-18 D. S. Simon , A. V. Sergienko

An interferometric fluorescent microscope and a novel theoretic image reconstruction approach were developed and used to obtain super-resolution images of live biological samples and to enable dynamic real time tracking. The tracking…

Interferometric-based microscopies stand as powerful label-free approaches for monitoring and characterising chemical reactions and heterogeneous nanoparticle systems in real time with single particle sensitivity. Nevertheless, coherent…

Structured Illumination Microscopy is a widespread methodology to image live and fixed biological structures smaller than the diffraction limits of conventional optical microscopy. Using recent advances in image up-scaling through deep…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Miguel Boland , Edward A. K. Cohen , Seth Flaxman , Mark A. A. Neil

We propose using interferometry of circularly polarized light as a mechanism by which to test for axion dark matter. These interferometers differ from standard interferometers only by the addition of a few quarter waveplates to preserve the…

High Energy Physics - Phenomenology · Physics 2018-08-22 William DeRocco , Anson Hook

Coherent interferometric scattering microscopy (iscat) enables nanoparticle tracking on microsecond timescales and with nanometer precision, and has become a key tool in structural and cellular biophysics. The achievable localization…

Improving axial resolution is crucial for three-dimensional optical imaging systems. Here we present a scheme of axial superresolution for two incoherent point sources based on spatial mode demultiplexing. A radial mode sorter is used to…

A microscope based on the Linnik interferometer was designed, built, and tested. Two methods were used for interference pattern measurement: phase-shifting and polarized single-shot methods. The former uses a low coherence light emitting…

Optics · Physics 2024-06-25 Sergei V. Anishchik , Marcos Dantus

Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…

The increase of resolution by the use of microspheres is related to the use of evanescent waves, satisfying complex Snell law where the trigonometric functions of the incident and refracted angles are complex trigonometric functions,…

Optics · Physics 2016-07-12 Y. Ben-Aryeh

The main advantage of two-photon fluorescence confocal microscopy is the low absorption obtained with live tissues at the wavelengths of operation. However, the resolution of two-photon fluorescence confocal microscopes is lower than in the…

Biological Physics · Physics 2009-11-13 N. Sandeau , H. Giovannini

Recent advances in optical imaging and communication increasingly involve high-dimensional, partially coherent light, creating a growing need for scalable tools to measure and manipulate coherence. Here, we demonstrate the automatic…

Improving axial resolution is of paramount importance for three-dimensional optical imaging systems. Here, we investigate the ultimate precision in axial localization using vortex beams. For Laguerre-Gauss beams, this limit can be achieved…

Quantum Physics · Physics 2021-03-09 D. Koutny , Z. Hradil , J. Rehacek , L. L. Sanchez-Soto

Precise measurement of the angular deviation of an object is a common task in science and technology. Many methods use light for this purpose. Some of these exploit interference effects to achieve technological advantages, such as…

Quantum Physics · Physics 2020-08-19 G. H. Aguilar , R. S. Piera , P. L. Saldanha , R. L. de Matos Filho , S. P. Walborn

Conoscopic interferometry is a promising detection technique for ultrafast acoustics. By focusing a probe beam through a birefringent crystal before passing it through a polarizer, conoscopic interferences sculpt the spatial profile of the…

Applied Physics · Physics 2022-11-08 Martin Robin , Ruben Guis , Mustafa Umit Arabul , Zili Zhou , Nitesh Pandey , Gerard J. Verbiest

Spatial resolution is one of the most important specifications of an imaging system. Recent results in quantum parameter estimation theory reveal that an arbitrarily small distance between two incoherent point sources can always be…

The Large Binocular Telescope Interferometer is a high contrast imager and interferometer that sits at the combined bent Gregorian focus of the LBT's dual 8.4~m apertures. The interferometric science drivers dictate 0.1'' resolution with…

Accurate distance measurement in 3D confocal microscopy is important for quantitative analysis, volume visualization and image restoration. However, axial distances can be distorted by both the point spread function and by a…

Soft Condensed Matter · Physics 2014-04-16 Thijs Herman Besseling , Jissy Jose , Alfons van Blaaderen
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