English

A minimal HIV-AIDS infection model with general incidence rate and application to Morocco data

Populations and Evolution 2019-08-12 v1 Classical Analysis and ODEs

Abstract

We study the global dynamics of a SICA infection model with general incidence rate. The proposed model is calibrated with cumulative cases of infection by HIV-AIDS in Morocco from 1986 to 2015. We first prove that our model is biologically and mathematically well-posed. Stability analysis of different steady states is performed and threshold parameters are identified where the model exhibits clearance of infection or maintenance of a chronic infection. Furthermore, we examine the robustness of the model to some parameter values by examining the sensitivity of the basic reproduction number. Finally, using numerical simulations with real data from Morocco, we show that the model predicts well such reality.

Keywords

Cite

@article{arxiv.1812.06965,
  title  = {A minimal HIV-AIDS infection model with general incidence rate and application to Morocco data},
  author = {El Mehdi Lotfi and Marouane Mahrouf and Mehdi Maziane and Cristiana J. Silva and Delfim F. M. Torres and Noura Yousfi},
  journal= {arXiv preprint arXiv:1812.06965},
  year   = {2019}
}

Comments

This is a preprint of a paper whose final and definite form is with 'Statistics Opt. Inform. Comput.', Vol. 7, No 2 (2019). See [http://www.IAPress.org]. Submitted 16/Sept/2018; Revised 10 & 15/Dec/2018; Accepted 15/Dec/2018