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A data-driven Reduced Order Method for parametric optimal blood flow control: application to coronary bypass graft

Medical Physics 2022-07-01 v1 Computational Engineering, Finance, and Science

Abstract

We consider an optimal flow control problem in a patient-specific coronary artery bypass graft with the aim of matching the blood flow velocity with given measurements as the Reynolds number varies in a physiological range. Blood flow is modelled with the steady incompressible Navier-Stokes equations. The geometry consists in a stenosed left anterior descending artery where a single bypass is performed with the right internal thoracic artery. The control variable is the unknown value of the normal stress at the outlet boundary, which is need for a correct set-up of the outlet boundary condition. For the numerical solution of the parametric optimal flow control problem, we develop a data-driven reduced order method that combines proper orthogonal decomposition (POD) with neural networks. We present numerical results showing that our data-driven approach leads to a substantial speed-up with respect to a more classical POD-Galerkin strategy proposed in [59], while having comparable accuracy.

Keywords

Cite

@article{arxiv.2206.15384,
  title  = {A data-driven Reduced Order Method for parametric optimal blood flow control: application to coronary bypass graft},
  author = {Caterina Balzotti and Pierfrancesco Siena and Michele Girfoglio and Annalisa Quaini and Gianluigi Rozza},
  journal= {arXiv preprint arXiv:2206.15384},
  year   = {2022}
}
R2 v1 2026-06-24T12:09:57.481Z