We discuss two aspects, the in vivo and in vitro difference and the modeling of noise, of integrative modeling of network dynamics in biology, using phage lambda as an example. We believe those two aspects have not been seriously considered, and the including of them may be enough to solve the outstanding stability and robustness puzzle of in gene regulatory network dynamics.
@article{arxiv.cond-mat/0307747,
title = {Towards the Understanding of Stability Puzzles in Phage lambda},
author = {P. Ao and L. Yin},
journal= {arXiv preprint arXiv:cond-mat/0307747},
year = {2007}
}