Monte Carlo (MC) techniques are currently deemed the gold standard for internal dosimetry, since the simulations can perform full radiation transport and reach a precision level not attainable by analytical methods. In this study, a custom voxelized particle source was developed for the TOPAS-MC toolkit to be used for internal dosimetry purposes. The source was designed to allow the use of clinical functional scans data to simulate events that reproduce the patient-specific tracer biodistribution. Simulation results are very promising, showing that this can be a first step towards the extension of TOPAS-MC to nuclear medicine applications. In the future more studies are needed to further ascertain the applicability and accuracy of the developed routines.
@article{arxiv.2306.03657,
title = {TOPAS-MC Extension for Nuclear Medicine Applications},
author = {Cristiana Rodrigues and Luis Peralta and Paulo Ferreira},
journal= {arXiv preprint arXiv:2306.03657},
year = {2023}
}