Single-molecule pulling: phenomenology and interpretation
Biological Physics
2013-02-19 v2 Soft Condensed Matter
Statistical Mechanics
Chemical Physics
Abstract
Single-molecule pulling techniques have emerged as versatile tools for probing the noncovalent forces holding together the secondary and tertiary structure of macromolecules. They also constitute a way to study at the single-molecule level processes that are familiar from our macroscopic thermodynamic experience. In this Chapter, we summarize the essential phenomenology that is typically observed during single-molecule pulling, provide a general statistical mechanical framework for the interpretation of the equilibrium force spectroscopy and illustrate how to simulate single-molecule pulling experiments using molecular dynamics.
Cite
@article{arxiv.1205.5068,
title = {Single-molecule pulling: phenomenology and interpretation},
author = {Ignacio Franco and Mark A. Ratner and George C. Schatz},
journal= {arXiv preprint arXiv:1205.5068},
year = {2013}
}
Comments
arXiv admin note: text overlap with arXiv:0908.2208