Semiparametric imputation using latent sparse conditional Gaussian mixtures for multivariate mixed outcomes

This paper proposes a flexible Bayesian approach to multiple imputation using conditional Gaussian mixtures. We introduce novel shrinkage priors for covariate-dependent mixing proportions in the mixture models to automatically select the suitable number of components used in the imputation step. We develop an efficient sampling algorithm for posterior computation and multiple imputation via Markov Chain Monte Carlo methods. The proposed method can be easily extended to the situation where the data contains not only continuous variables but also discrete variables such as binary and count values. We also propose approximate Bayesian inference for parameters defined by loss functions based on posterior predictive distributing of missing observations, by extending bootstrap-based Bayesian inference for complete data. The proposed method is demonstrated through numerical studies using simulated and real data.