On a generalized false discovery rate
Abstract
The concept of -FWER has received much attention lately as an appropriate error rate for multiple testing when one seeks to control at least false rejections, for some fixed . A less conservative notion, the -FDR, has been introduced very recently by Sarkar [Ann. Statist. 34 (2006) 394--415], generalizing the false discovery rate of Benjamini and Hochberg [J. Roy. Statist. Soc. Ser. B 57 (1995) 289--300]. In this article, we bring newer insight to the -FDR considering a mixture model involving independent -values before motivating the developments of some new procedures that control it. We prove the -FDR control of the proposed methods under a slightly weaker condition than in the mixture model. We provide numerical evidence of the proposed methods' superior power performance over some -FWER and -FDR methods. Finally, we apply our methods to a real data set.
Keywords
Cite
@article{arxiv.0906.3091,
title = {On a generalized false discovery rate},
author = {Sanat K. Sarkar and Wenge Guo},
journal= {arXiv preprint arXiv:0906.3091},
year = {2009}
}
Comments
Published in at http://dx.doi.org/10.1214/08-AOS617 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)