Neighbor joining with phylogenetic diversity estimates
Quantitative Methods
2007-05-23 v1 Combinatorics
Abstract
The Neighbor-Joining algorithm is a recursive procedure for reconstructing trees that is based on a transformation of pairwise distances between leaves. We present a generalization of the neighbor-joining transformation, which uses estimates of phylogenetic diversity rather than pairwise distances in the tree. This leads to an improved neighbor-joining algorithm whose total running time is still polynomial in the number of taxa. On simulated data, the method outperforms other distance-based methods. We have implemented neighbor-joining for subtree weights in a program called MJOIN which is freely available under the Gnu Public License at http://bio.math.berkeley.edu/mjoin/ .
Cite
@article{arxiv.q-bio/0508001,
title = {Neighbor joining with phylogenetic diversity estimates},
author = {Dan Levy and Ruriko Yoshida and Lior Pachter},
journal= {arXiv preprint arXiv:q-bio/0508001},
year = {2007}
}