The relevant length scales for superconductivity are of the order of nanometers. By confining the superconducting condensate to such dimensions, many physical properties change substantially, and novel phenomena emerge, which are absent in the pristine material. We discuss various methods of creating artificial nanostructures by top-down approaches in metallic and copper-oxide superconductors and their applications. Such nanostructures can be used to control magnetic flux quanta in superconductors, anchoring them to engineered defects to avoid dissipation, guiding their motion, or building artificial flux-quanta arrangements. Nanopatterned superconductors are essential for creating model systems for basic research and enable building almost dissipationless and ultrafast electronic devices and highly sensitive sensors.