More than 30 years ago, we published a paper entitled as abnormal chromatin configuration and oncogenesis, which proposed the first hypothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis is presented.
Cite
@article{arxiv.1901.04432,
title = {Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis},
author = {Gao-De Li},
journal= {arXiv preprint arXiv:1901.04432},
year = {2019}
}