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Expert-Guided POMDP Learning for Data-Efficient Modeling in Healthcare

Machine Learning 2025-11-19 v1 Artificial Intelligence

Abstract

Learning the parameters of Partially Observable Markov Decision Processes (POMDPs) from limited data is a significant challenge. We introduce the Fuzzy MAP EM algorithm, a novel approach that incorporates expert knowledge into the parameter estimation process by enriching the Expectation Maximization (EM) framework with fuzzy pseudo-counts derived from an expert-defined fuzzy model. This integration naturally reformulates the problem as a Maximum A Posteriori (MAP) estimation, effectively guiding learning in environments with limited data. In synthetic medical simulations, our method consistently outperforms the standard EM algorithm under both low-data and high-noise conditions. Furthermore, a case study on Myasthenia Gravis illustrates the ability of the Fuzzy MAP EM algorithm to recover a clinically coherent POMDP, demonstrating its potential as a practical tool for data-efficient modeling in healthcare.

Keywords

Cite

@article{arxiv.2511.14619,
  title  = {Expert-Guided POMDP Learning for Data-Efficient Modeling in Healthcare},
  author = {Marco Locatelli and Arjen Hommersom and Roberto Clemens Cerioli and Daniela Besozzi and Fabio Stella},
  journal= {arXiv preprint arXiv:2511.14619},
  year   = {2025}
}
R2 v1 2026-07-01T07:43:38.586Z