Evaluation of blood coagulation by optical vortex tracking
Abstract
We investigated a new optical approach for the detection of the coagulation dynamic process by means of the information on the optical vortex. In our study, laser speckle was captured using a high-speed CMOS camera, and the statistical information of the optical vortex characterized the change in coagulation properties with time. Similar to the scattering particles, the motion of the optical vortex is restricted during coagulation, as a result, the whole process of coagulation can be detected by calculating the mean square displacement(MSD) of the optical vortex. The results demonstrate a close correlation between coagulation parameters measured using the optical vortex method and thrombelastography(TEG), creating a powerful opportunity for self-testing and real-time detection of coagulation.
Keywords
Cite
@article{arxiv.2105.09306,
title = {Evaluation of blood coagulation by optical vortex tracking},
author = {Yaowen Zhang and Jiaxing Gong and Hui Zhang and Qi Li and Guangbin Ren and Wenjian Lu and Jing Wang},
journal= {arXiv preprint arXiv:2105.09306},
year = {2021}
}