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Estimation of within-study covariances in multivariate meta-analysis

Methodology 2020-03-12 v1 Numerical Analysis Numerical Analysis Quantitative Methods Applications

Abstract

Multivariate meta-analysis can be adapted to a wide range of situations for multiple outcomes and multiple treatment groups when combining studies together. The within-study correlation between effect sizes is often assumed known in multivariate meta-analysis while it is not always known practically. In this paper, we propose a generic method to approximate the within-study covariance for effect sizes in multivariate meta-analysis and apply this method to the scenarios with multiple outcomes and one outcome with multiple treatment groups respectively.

Keywords

Cite

@article{arxiv.2003.05092,
  title  = {Estimation of within-study covariances in multivariate meta-analysis},
  author = {Xiaohuan Xue},
  journal= {arXiv preprint arXiv:2003.05092},
  year   = {2020}
}
R2 v1 2026-06-23T14:11:03.313Z