English

DNA Unzipping Transition

Soft Condensed Matter 2025-09-16 v2 Statistical Mechanics

Abstract

This review focuses on the force-induced unzipping transition of double-stranded DNA. It begins with a brief history of DNA melting, which emerged alongside the growth of the field of molecular biology, juxtaposed with the advancements in physics during the same post-World War II period. The earlier theories of melting of DNA were based on the Ising model and its modifications, but gradually moved towards polymer-based models. The idea of force-induced unzipping was first introduced in 1999 as a cooperative mechanism for breaking base pairs without the need for temperature changes. The paper discusses several subsequent developments addressing different aspects of the unzipping transition.

Keywords

Cite

@article{arxiv.2506.24064,
  title  = {DNA Unzipping Transition},
  author = {Somendra M. Bhattacharjee},
  journal= {arXiv preprint arXiv:2506.24064},
  year   = {2025}
}

Comments

For EPJ B Topical Issue: 100 Glorious Years of the Ising Model

R2 v1 2026-07-01T03:39:54.074Z