Detection of cellular micromotion by advanced signal processing
Image and Video Processing
2021-06-24 v2 Biological Physics
Abstract
Cellular micromotion - a tiny movement of cell membranes on the nanometer-micrometer scale - has been proposed as a pathway for inter-cellular signal transduction and as a label-free proxy signal to neural activity. Here we harness several recent approaches of signal processing to detect such micromotion in video recordings of unlabeled cells. Our survey includes spectral filtering of the video signal, matched filtering, as well as 1D and 3D convolutional neural networks acting on pixel-wise time-domain data and a whole recording respectively.
Cite
@article{arxiv.2005.06016,
title = {Detection of cellular micromotion by advanced signal processing},
author = {Stephan Rinner and Alberto Trentino and Heike Url and M. Florian G. Burger and Julian von Lautz and Bernhard Wolfrum and Friedemann Reinhard},
journal= {arXiv preprint arXiv:2005.06016},
year = {2021}
}