In this Master's thesis, the graph properties of a multi-level drug-protein network are studied, as well as how the network's shape has informed discoveries over the years, identifying primarily crawling discoveries and a smaller number of hopping discoveries. Finally, the network structure is used to inform a network diffusion recommendation system and to prioritize existing drugs for repurposing against proteins in organisms that cause Neglected Tropical Diseases.
@article{arxiv.2602.23396,
title = {Complex Networks and the Drug Repositioning Problem},
author = {Felipe Bivort Haiek},
journal= {arXiv preprint arXiv:2602.23396},
year = {2026}
}