We have completed a lattice QCD calculation of ΔmK, the mass difference between the long- and short-lived K mesons. The calculation was performed on a 643×128 lattice using 152 configurations with physical quark masses and an inverse lattice spacing of 1/a=2.36 GeV. While the statistical error approaches a relatively small size of 9%, several sources of systematic errors may have more significant effects. In this paper we will address studies performed on smaller lattices to estimate the systematic errors in our result.