English

Bacterial phylogeny in the Cayley graph

Group Theory 2016-01-19 v1 Populations and Evolution Quantitative Methods

Abstract

Many models of genome rearrangement involve operations (e.g. inversions and translocations) that are self-inverse, and hence generate a group acting on the space of genomes. This gives a correspondence between genome arrangements and the elements of a group, and consequently, between evolutionary paths and walks on the Cayley graph. Many common methods for phylogeny reconstruction rely on calculating the minimal distance between two genomes; this omits much of the other information available from the Cayley graph. In this paper we begin an exploration of some of this additional information, in particular describing the phylogeny as a Steiner tree within the Cayley graph, and exploring the "interval" between two genomes. While motivated by problems in systematic biology, many of these ideas are of independent group-theoretic interest.

Keywords

Cite

@article{arxiv.1601.04398,
  title  = {Bacterial phylogeny in the Cayley graph},
  author = {Chad Clark and Attila Egri-Nagy and Andrew R. Francis and Volker Gebhardt},
  journal= {arXiv preprint arXiv:1601.04398},
  year   = {2016}
}

Comments

9 pages, 6 figures, final version will be published elsewhere

R2 v1 2026-06-22T12:31:24.853Z