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Related papers: A Non-critical String (Liouville) Approach to Brai…

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Microtubule (MT) networks, subneural paracrystalline cytosceletal structures, seem to play a fundamental role in the neurons. We cast here the complicated MT dynamics in the form of a $1+1$-dimensional non-critical string theory, thus…

High Energy Physics - Phenomenology · Physics 2008-02-03 N. Mavromatos , D. Nanopoulos

In this talk we review recent work on integrable models for Microtubule (MT) networks, subneural paracrystalline cytosceletal structures, which seem to play a fundamental role in the neurons. We cast here the complicated MT dynamics in the…

Quantum Physics · Physics 2007-05-23 N. E. Mavromatos , D. V. Nanopoulos

We review certain aspects of brain function which could be associated with non-critical (Liouville) string theory. In particular we simulate the physics of brain microtubules (MT) by using a (completely integrable) non-critical string, we…

Quantum Physics · Physics 2007-05-23 N. E. Mavromatos , D. V. Nanopoulos

Recent developments/efforts to understand aspects of the brain function at the {\em sub-neural} level are discussed. MicroTubules (MTs) participate in a wide variety of dynamical processes in the cell, especially in bioinformation processes…

High Energy Physics - Phenomenology · Physics 2007-05-23 D. Nanopoulos

Critical String Theory is by definition an $S$-matrix theory. In this sense, (quantum) gravity situations where a unitary $S$-matrix may not be a well-defined concept, as a consequence of the existence of macroscopic (global) or microscopic…

High Energy Physics - Theory · Physics 2007-05-23 Elias Gravanis , Nick E. Mavromatos

In order to create a novel model of memory and brain function, we focus our approach on the sub-molecular (electron), molecular (tubulin) and macromolecular (microtubule) components of the neural cytoskeleton. Due to their size and…

Quantum Physics · Physics 2007-05-23 A. Mershin , D. V. Nanopoulos , E. M. C. Skoulakis

We formulate and study a quantum field theory of a microtubule, a basic element of living cells. Following the quantum theory of consciousness by Hameroff and Penrose, we let the system to reduce to one of the classical states without…

Quantum Physics · Physics 2008-09-08 Takashi Hiramatsu , Tetsuo Matsui , Kazuhiko Sakakibara

A connection between non-perturbative formulations of quantum gravity and perturbative string theory is exhibited, based on a formulation of the non-perturbative dynamics due to Markopoulou. In this formulation the dynamics of spin network…

High Energy Physics - Theory · Physics 2009-10-31 Lee Smolin

Dynamic instability in the cytoskeleton underlies a great many vital cellular processes. In neurons, it is thought to play a role in information processing and the establishment of synaptic connections. It is from this interneuronal…

Medical Physics · Physics 2019-12-19 Gweneth Andersen

We focus on potential mechanisms for `energy-loss-free' transport along the cell microtubules, which could be considered as realizations of Fr\"ohlich's ideas on the role of solitons for superconductivity and/or biological matter. In…

Quantum Physics · Physics 2007-05-23 N. E. Mavromatos , D. V. Nanopoulos

One of the leading candidates for quantum gravity, viz. string theory, has the following features incorporated in it. (i) The full spacetime is higher dimensional, with (possibly) compact extra-dimensions; (ii) There is a natural minimal…

High Energy Physics - Theory · Physics 2014-11-18 Michele Fontanini , Euro Spallucci , T. Padmanabhan

It has become increasingly evident that fabrication of novel biomaterials through molecular self-assembly is going to play a significant role in material science and possibly the information technology of the future. Tubulin, microtubules…

In the mid-1990s it was proposed that quantum effects in proteins known as microtubules play a role in the nature of consciousness. The theory was largely dismissed due to the fact that quantum effects were thought unlikely to occur in…

Neurons and Cognition · Quantitative Biology 2019-10-21 Betony Adams , Francesco Petruccione

We propose the use of the ``spin-opstring", derived from Stochastic Series Expansion Quantum Monte Carlo (QMC) simulations as machine learning (ML) input data. It offers a compact, memory-efficient representation of QMC simulation cells,…

Strongly Correlated Electrons · Physics 2025-11-05 Amrita Ghosh , Mugdha Sarkar , Ying-Jer Kao , Pochung Chen

We discuss possible quantum mechanical aspects of MicroTubules (MT), based on recent developments in quantum physics.We focus on potential mechanisms for `energy-loss-free' transport along the microtubules, which could be considered as…

Quantum Physics · Physics 2009-10-30 N. E. Mavromatos , D. V. Nanopoulos

We present a coarse-grained two dimensional mechanical model for the microtubule-tau bundles in neuronal axons in which we remove taus, as can happen in various neurodegenerative conditions such as Alzheimer's disease, tauopathies, and…

Neurons and Cognition · Quantitative Biology 2014-10-01 Austin Sendek , Henry R. Fuller , N. Robert Hayre , Rajiv R. P. Singh , Daniel L. Cox

The microtubule cytoskeleton is responsible for sustained, long-range intracellular transport of mRNAs, proteins, and organelles in neurons. Neuronal microtubules must be stable enough to ensure reliable transport, but they also undergo…

Dynamical Systems · Mathematics 2024-03-05 Anna C Nelson , Melissa M Rolls , Maria-Veronica Ciocanel , Scott A McKinley

In the non-critical string framework that we have proposed recently, the time $t$ is identified with a dynamical local renormalization group scale, the Liouville mode, and behaves as a statistical evolution parameter, flowing irreversibly…

High Energy Physics - Theory · Physics 2007-05-23 J. Ellis , N. Mavromatos , D. Nanopoulos

Microtubules (MTs) are dynamic protein filaments essential for intracellular organization and transport, particularly in long-lived cells such as neurons. The plus and minus ends of neuronal MTs switch between growth and shrinking phases,…

Biological Physics · Physics 2025-07-11 Anna C. Nelson , Scott A. McKinley , Melissa M. Rolls , Maria-Veronica Ciocanel

We investigate the presence of memory in the sequential measurement statistics of an open quantum system, as witnessed by the departure from the quantum regression theorem (QRT), that is, the possibility to predict multitime probabilities…

Quantum Physics · Physics 2026-05-08 Paolo Luppi , Claudia Benedetti , Andrea Smirne
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