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All living systems can function only far away from equilibrium, and for this reason chemical kinetic methods are critically important for uncovering the mechanisms of biological processes. Here we present a new theoretical method of…

Subcellular Processes · Quantitative Biology 2018-04-27 Maria P. Kochugaeva , Alexey A. Shvets , Anatoly B. Kolomeisky

Proteins are the common constituents of all living cells. They are molecular machines that interact with each other as well as with other cell products and carry out a dizzying array of functions with distinction. These interactions follow…

Biomolecules · Quantitative Biology 2022-05-25 Tatjana Škrbić , Trinh Xuan Hoang , Achille Giacometti , Amos Maritan , Jayanth R. Banavar

This paper links the conjecture that the physical world is a virtual reality to the findings of modern physics. What is usually the subject of science fiction is here proposed as a scientific theory open to empirical evaluation. We know…

Other Computer Science · Computer Science 2010-11-16 B. Whitworth

We apply the theory of learning to physically renormalizable systems in an attempt to develop a theory of biological evolution, including the origin of life, as multilevel learning. We formulate seven fundamental principles of evolution…

Populations and Evolution · Quantitative Biology 2022-10-12 Vitaly Vanchurin , Yuri I. Wolf , Mikhail I. Katsnelson , Eugene V. Koonin

These are notes for a set of 7 two-hour lectures given at the 2010 Summer School on Quantitative Evolutionary and Comparative Genomics at OIST, Okinawa, Japan. The emphasis is on understanding how biological systems process information. We…

Molecular Networks · Quantitative Biology 2010-06-23 Gašper Tkačik

Quantum mechanics, one of the most successful theories in the history of science, was created to account for physical systems not describable by classical physics. Though it is consistent with all experiments conducted thus far, many of its…

Quantum Physics · Physics 2016-02-17 Gary Oas , J. Acacio de Barros

Questions concerning origin of mathematical knowledge and roles of language and intuition (imagery) in mathematical thoughts are long standing and widely debated. By introspection, mathematicians usually have some beliefs regarding these…

Neurons and Cognition · Quantitative Biology 2019-10-02 Manouchehr Zaker

Discovering physical laws directly from high-dimensional visual data is a long-standing human pursuit but remains a formidable challenge for machines, representing a fundamental goal of scientific intelligence. This task is inherently…

Computational Engineering, Finance, and Science · Computer Science 2026-02-24 Ruikun Li , Jun Yao , Yingfan Hua , Shixiang Tang , Biqing Qi , Bin Liu , Wanli Ouyang , Yan Lu

This essay considers a simple model of observers that are influenced by the world around them. Consistent quantification of information about such influences results in a great deal of familiar physics. The end result is a new perspective…

Quantum Physics · Physics 2013-08-16 Kevin H. Knuth

The image of physics is connected with simple "mechanical" deterministic events: that an apple always falls down, that force equals mass times acceleleration. Indeed, applications of such concept to social or historical problems go back two…

Popular Physics · Physics 2011-09-13 Dietrich Stauffer

It is argued that quantum mechanics follows naturally from the assumptions that there are no fundamental causal laws but only probabilities for physical processes that are constrained by symmetries, and reality is relational in the sense…

Quantum Physics · Physics 2014-11-18 Jeeva Anandan

A generalized understanding of protein dynamics is an unsolved scientific problem, the solution of which is critical to the interpretation of the structure-function relationships that govern essential biological processes. Here, we approach…

In recent years, the field of statistics has experienced a surge in interest and application, largely due to significant advances in computer technology. This progress has led to remarkable developments in statistics methods and algorithms,…

Other Statistics · Statistics 2023-10-03 M. M. Hammad

Algorithmic approach is based on the assumption that any quantum evolution of many particle system can be simulated on a classical computer with the polynomial time and memory cost. Algorithms play the central role here but not the…

Quantum Physics · Physics 2007-05-23 Yuri Ozhigov

The basic physics disciplines of Maxwell's electrodynamics and Newton's mechanics have been thoroughly tested in the laboratory, but they can nevertheless also support nonphysical solutions. The unphysical nature of some dynamical…

General Physics · Physics 2019-11-13 H. R. Reiss

In a first course to classical mechanics elementary physical processes like elastic two-body collisions, the mass-spring model, or the gravitational two-body problem are discussed in detail. The continuation to many-body systems, however,…

Physics Education · Physics 2014-03-10 Thomas Müller

Biological phenomena differ significantly from physical phenomena. At the heart of this distinction is the fact that biological entities have computational abilities and thus they are inherently difficult to predict. This is the reason why…

Molecular Networks · Quantitative Biology 2009-09-29 Pau Fernandez , Ricard V. Sole

Some contemporary views of the universe assume information and computation to be key in understanding and explaining the basic structure underpinning physical reality. We introduce the Computable Universe exploring some of the basic…

Information Theory · Computer Science 2012-06-05 Hector Zenil

Complex systems, such as life and languages, are governed by principles of evolution. The analogy and comparison between biology and linguistics\cite{alphafold2, RoseTTAFold, lang_virus, cell language, faculty1, language of gene, Protein…

Populations and Evolution · Quantitative Biology 2026-03-18 Li-Min Wang , Hsing-Yi Lai , Sun-Ting Tsai , Chen Siang Ng , Kevin Sheng-Kai Ma , Shan-Jyun Wu , Meng-Xue Tsai , Yi-Ching Su , Daw-Wei Wang , Tzay-Ming Hong

Quantum mechanics is a fundamentally probabilistic theory (at least so far as the empirical predictions are concerned). It follows that, if one wants to properly understand quantum mechanics, it is essential to clearly understand the…

Quantum Physics · Physics 2009-11-10 D. M. Appleby