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Quantifying stochastic processes is essential to understand many natural phenomena, particularly in biology, including cell-fate decision in developmental processes as well as genesis and progression of cancers. While various attempts have…

Statistical Mechanics · Physics 2017-06-28 Ying Tang , Ruoshi Yuan , Gaowei Wang , Xiaomei Zhu , Ping Ao

In complex systems, the interplay between nonlinear and stochastic dynamics, e.g., J. Monod's necessity and chance, gives rise to an evolutionary process in Darwinian sense, in terms of discrete jumps among attractors, with punctuated…

Adaptation and Self-Organizing Systems · Physics 2013-03-18 Hong Qian

Statistical physics provides a useful perspective for the analysis of many complex systems; it allows us to relate microscopic fluctuations to macroscopic observations. Developmental biology, but also cell biology more generally, are…

Cell Behavior · Quantitative Biology 2020-11-10 Anissa Guillemin , Michael P. H. Stumpf

The study of the physical properties of open quantum systems is at the heart of many present investigations which aim to describe their dynamical evolution, on theoretical ground and through physical realizations. Here we develop a…

Quantum Physics · Physics 2021-11-23 Tarek Khalil , Jean Richert

Recent work in dynamical systems theory has shown that many properties that are associated with irreversible processes in fluids can be understood in terms of the dynamical properties of reversible, Hamiltonian systems. That is,…

chao-dyn · Physics 2015-06-24 J. R. Dorfman

Dynamics near and far away from thermal equilibrium is studied within the framework of Langevin equations. A stochasticity-dissipation relation is proposed to emphasize the equal importance of the stochastic and deterministic forces in…

Classical Physics · Physics 2007-05-23 P. Ao

A stochastic dynamics framework for the study of complex systems is presented.

Statistical Mechanics · Physics 2007-05-23 L. S. Schulman , B. Gaveau

Some problems in the theory and applications of stochastic processes can be reduced to solving integral equations. While explicit solutions for these equations are often elusive, valuable insights can be gained through their asymptotic…

Probability · Mathematics 2024-11-28 P. Chigansky , M. Kleptsyna

The construction of effective and informative landscapes for stochastic dynamical systems has proven a long-standing and complex problem. In many situations, the dynamics may be described by a Langevin equation while constructing a…

Optimization and Control · Mathematics 2018-09-12 Rowan D Brackston , Andrew Wynn , Michael P H Stumpf

In order to better understand the occurrence of phase transitions, we adopt an approach based on the study of energy landscapes: The relation between stationary points of the potential energy landscape of a classical many-particle system…

Statistical Mechanics · Physics 2009-03-24 Michael Kastner

The state of many physical, biological and socio-technical systems evolves by combining smooth local transitions and abrupt resetting events to a set of reference values. The inclusion of the resetting mechanism not only provides the…

Statistical Mechanics · Physics 2022-12-21 Oriol Artime

Agent-based stochastic models for finite populations have recently received much attention in the game theory of evolutionary dynamics. Both the ultimate fixation and the pre-fixation transient behavior are important to a full understanding…

Populations and Evolution · Quantitative Biology 2015-03-17 Da Zhou , Hong Qian

Many real-world systems exhibit ``noisy'' evolution in time; interpreting their finitely-sampled behavior as arising from continuous-time processes (in the It\^o or Stratonovich sense) has led to significant success in modeling and analysis…

Mathematical Physics · Physics 2025-07-29 David Sabin-Miller , Daniel M. Abrams

We formulate a geometric measurement theory of dynamical classical systems possessing both continuous and discrete degrees of freedom. The approach is covariant with respect to choices of clocks and canonically incorporates laboratories.…

Mathematical Physics · Physics 2023-11-13 Subhobrata Chatterjee , Andrew Waldron , Cem Yetişmişoğlu

The existence of the {\em typical set} is key for data compression strategies and for the emergence of robust statistical observables in macroscopic physical systems. Standard approaches derive its existence from a restricted set of…

Statistical Mechanics · Physics 2022-02-10 Rudolf Hanel , Bernat Corominas-Murtra

Random walks on multidimensional nonlinear landscapes are of interest in many areas of science and engineering. In particular, properties of adaptive trajectories on fitness landscapes determine population fates and thus play a central role…

Populations and Evolution · Quantitative Biology 2014-10-08 Michael Manhart , Alexandre V. Morozov

This paper attempts to make feasible the evolutionary emergence of novelty in a supposedly deterministic world which behavior is associated with those of the mathematical dynamical systems. The work was motivated by the observation of…

Adaptation and Self-Organizing Systems · Physics 2024-06-26 R. Herrero , F. Pi , J. Rius , G. Orriols

This paper introduces several new classes of mathematical structures that have close connections with physics and with the theory of dynamical systems. The most general of these structures, called indivisible stochastic processes,…

Quantum Physics · Physics 2026-02-09 Jacob A. Barandes

Systems with a complex dynamics like glasses or models of biological evolution are often pictured in terms of complex landscapes, with a large number of possible collective states. We show on the example of a stochastic spin model with…

Disordered Systems and Neural Networks · Physics 2026-02-03 Laura Guislain , Eric Bertin

We develop a landscape-flux framework to investigate observed frequency distributions of vegetation and the stability of these ecological systems under fluctuations. The frequency distributions can characterize the population-potential…

Populations and Evolution · Quantitative Biology 2022-10-12 Li Xu , Denis Patterson , Ann Carla Staver , Simon Asher Levin , Jin Wang
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