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The sexual version of the Penna model of biological ageing, simulated since 1996, is compared here with alternative forms of reproduction as well as with models not involving ageing. In particular we want to check how sexual forms of life…

Statistical Mechanics · Physics 2007-05-23 D. Stauffer , P. M. C. de Oliveira , S. Moss de Oliveira , T. J. P. Penna , J. S. Sa' Martins

Retirement prediction helps individuals and institutions make informed financial, lifestyle, and workforce decisions based on estimated retirement portfolios. This paper attempts to predict retirement using Monte Carlo simulations, allowing…

Portfolio Management · Quantitative Finance 2023-11-22 Aditya Gupta , Vijay K. Tayal

Modifying the Redfield model of sexual reproduction and the Penna model of biological aging, we compare reproduction with and without recombination in age-structured populations. In contrast to Redfield and in agreement with Bernardes we…

We have simulated demographic changes in the human population using the Penna microscopic model, based on the simple Monte Carlo method. The results of simulations have shown that during a few generations changes in the genetic pool of a…

Statistical Mechanics · Physics 2007-05-23 A. Laszkiewicz , Sz. Szymczak , S. Cebrat

Monte Carlo simulations are based on the manipulation of random numbers to evaluate probable outcomes, with applicability in a variety of different fields. By assigning probabilities, which can be determined a priori, to various events, it…

Physics Education · Physics 2022-01-03 Parasuraman Swaminathan

The Penna model is a strategy to simulate the genetic dynamics of age-structured populations, in which the individuals genomes are represented by bit-strings. It provides a simple metaphor for the evolutionary process in terms of the…

Populations and Evolution · Quantitative Biology 2009-11-11 Veit Schwämmle , Suzana M. de Oliveira

This review deals with computer simulation of biological ageing, particularly with the Penna model of 1995.

Populations and Evolution · Quantitative Biology 2007-06-22 D. Stauffer

We describe the simulation method of modelling the population evolution using Monte Carlo based on the Penna model. Individuals in the populations are represented by their diploid genomes. Genes expressed after the minimum reproduction age…

Genomics · Quantitative Biology 2009-01-13 Agnieszka Laszkiewicz , Przemyslaw Biecek , Katarzyna Bonkowska , Stanislaw Cebrat

The paper presents an investigation of estimating treatment effect using different matching methods. The study proposed a new method which is computationally efficient and convenient in implication-'largest caliper matching' and compared…

Applications · Statistics 2018-06-07 Sharif Mahmood

For many complex simulation tasks spanning areas such as healthcare, engineering, and finance, Monte Carlo (MC) methods are invaluable due to their unbiased estimates and precise error quantification. Nevertheless, Monte Carlo simulations…

As the size of engineered systems grows, problems in reliability theory can become computationally challenging, often due to the combinatorial growth in the cut sets. In this paper we demonstrate how Multilevel Monte Carlo (MLMC) - a…

Computation · Statistics 2017-03-14 Louis J. M. Aslett , Tigran Nagapetyan , Sebastian J. Vollmer

In this paper, we present a two-stage stochastic international portfolio optimisation model to find an optimal allocation for the combination of both assets and currency hedging positions. Our optimisation model allows a "currency overlay",…

Computational Engineering, Finance, and Science · Computer Science 2017-04-06 Nonthachote Chatsanga , Andrew J. Parkes

Monte Carlo computer simulations are virtually the only way to analyze the thermodynamic behavior of a system in a precise way. However, the various existing methods exhibit extreme differences in their efficiency, depending on model…

Statistical Mechanics · Physics 2011-07-05 Michael Bachmann

We discuss suitable classes of diffusion processes, for which functionals relevant to finance can be computed via Monte Carlo methods. In particular, we construct exact simulation schemes for processes from this class. However, should the…

Numerical Analysis · Mathematics 2012-04-06 Jan Baldeaux , Eckhard Platen

This paper examines the use of Monte Carlo simulations to understand statistical concepts in A/B testing and Randomized Controlled Trials (RCTs). We discuss the applicability of simulations in understanding false positive rates and estimate…

Applications · Statistics 2024-11-12 Márton Trencséni

Cellular senescence is thought to play a major role in age-related diseases, which cause nearly 67% of all human deaths worldwide. Recent research in mice showed that exercising mice had higher levels of telomerase, an enzyme that helps…

Populations and Evolution · Quantitative Biology 2013-11-13 Avikar Periwal

Computer hardware costs are the limiting factor in producing highly accurate radiation dose calculations on convenient time scales. Because of this, large-scale, full Monte Carlo simulations and other resource intensive algorithms are often…

Medical Physics · Physics 2010-09-28 Roy W. Keyes , Christian Romano , Dorian Arnold , Shuang Luan

In this paper the Penna model is reconsidered. With computer simulations we check how the control parameters of the model influence the size of the stable population.

Populations and Evolution · Quantitative Biology 2007-05-23 K. Malarz , M. Sitarz , P. Gronek , A. Dydejczyk

Multiple hypothesis tests are often carried out in practice using p-value estimates obtained with bootstrap or permutation tests since the analytical p-values underlying all hypotheses are usually unknown. This article considers the…

Computation · Statistics 2019-10-08 Georg Hahn

Independently estimating pixel values in Monte Carlo rendering results in a perceptually sub-optimal white-noise distribution of error in image space. Recent works have shown that perceptual fidelity can be improved significantly by…

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