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Dynamics of biological-ecological systems is strongly depending on spatial dimensions. Most of powerful simulators in ecology take into account for system spatiality thus embedding stochastic processes. Due to the difficulty of researching…
Bistability is ubiquitous in biological systems. For example, bistability is found in many reaction networks that involve the control and execution of important biological functions, such as signalling processes. Positive feedback loops,…
Many systems in biology, physics, and engineering are modeled by nonlinear dynamical systems where the states are usually unknown and only a subset of the state variables can be physically measured. Can we understand the full system from…
Receptor-induced apoptosis is a complex signal transduction pathway involving numerous protein/protein interactions and post-transcriptional modifications. The response to death receptor stimulation varies significantly from one cell line…
Nano-mechanical resonators have gained an increasing importance in nanotechnology owing to their contributions to both fundamental and applied science. Yet, their small dimensions and mass raises some challenges as their dynamics gets…
Complex industrial processes such as the drying of combustible biomass can be modeled with computational fluid dynamics simulations. Due to their complexity, it is not straightforward to use these models for the analysis of system…
The prospect of a system possessing two or more stable states for a given excitation condition is of topical interest with applications in information processing networks. In this work, we establish the remote transfer of bistability from a…
Large-scale network systems describe a wide class of complex dynamical systems composed of many interacting subsystems. A large number of subsystems and their high-dimensional dynamics often result in highly complex topology and dynamics,…
Despite their deterministic nature, dynamical systems often exhibit seemingly random behaviour. Consequently, a dynamical system is usually represented by a probabilistic model of which the unknown parameters must be estimated using…
Self-organized bistability (SOB) stands as a critical behavior for the systems delicately adjusting themselves to the brink of bistability, characterized by a first-order transition. Its essence lies in the inherent ability of the system to…
This work concerns the question of how two important dynamical properties, oscillations and bistability, emerge in an important biological signaling network. Specifically, we consider a model for dual-site phosphorylation and…
Several coupled maps models are sketched and reviewed in this short communication. First, a discrete logistic type model that was proposed for the symbiotic interaction of two species. Second, a model of many of these symbiotic species…
Necessary conditions for asymptotic stability and stabilizability of subsets for dynamical and control systems are obtained. The main necessary condition is homotopical and is in turn used to obtain a homological one. A certain extension is…
Time-discrete dynamical systems on a finite state space have been used with great success to model natural and engineered systems such as biological networks, social networks, and engineered control systems. They have the advantage of being…
Mathematical modelling allows us to concisely describe fundamental principles in biology. Analysis of models can help to both explain known phenomena, and predict the existence of new, unseen behaviours. Model analysis is often a complex…
The galactose network is a complex system responsible for galactose metabolism. It has been extensively studied experimentally and mathematically at the unicellular level to broaden our understanding of its regulatory mechanisms at higher…
Model selection methods are used in different scientific contexts to represent a characteristic data set in terms of a reduced number of parameters. Apparently, these methods have not found their way into the literature on multibody systems…
Networked systems are systems of interconnected components, in which the dynamics of each component are influenced by the behavior of neighboring components. Examples of networked systems include biological networks, critical…
For the nervous system to work at all, a delicate balance of excitation and inhibition must be achieved. However, when such a balance is sought by global strategies, only few modes remain balanced close to instability, and all other modes…
One of the aims of systems biology is to build multiple layered and multiple scale models of living systems which can efficiently describe phenomena occurring at various level of resolution. Such models should consist of layers of various…