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The two-point central difference is a common algorithm in biological signal processing and is particularly useful in analyzing physiological signals. In this paper, we develop a model-based classification method to detect epileptic seizures…

Applications · Statistics 2020-06-01 Antonio Quintero-Rincon , Carlos D'Giano , Hadj Batatia

Computing the autotopism group of a partial Latin rectangle can be performed in a variety of ways. This pilot study has two aims: (a) to compare these methods experimentally, and (b) to identify the design goals one should have in mind for…

Combinatorics · Mathematics 2021-06-18 Rebecca J. Stones , Raúl M. Falcón , Daniel Kotlar , Trent G. Marbach

Statistical hypothesis testing, as formalized by 20th Century statisticians and taught in college statistics courses, has been a cornerstone of 100 years of scientific progress. Nevertheless, the methodology is increasingly questioned in…

Methodology · Statistics 2024-08-22 Brian Dennis , Mark L Taper , José M Ponciano

An accurate multiclass classification strategy is crucial to interpreting antibody tests. However, traditional methods based on confidence intervals or receiver operating characteristics lack clear extensions to settings with more than two…

Quantitative Methods · Quantitative Biology 2024-05-07 Rayanne A. Luke , Anthony J. Kearsley , Paul N. Patrone

We compute exact solutions of two--matrix models, i.e. detailed genus by genus expressions for the correlation functions of these theories, calculated without any approximation. We distinguish between two types of models, the unconstrained…

High Energy Physics - Theory · Physics 2009-10-28 L. Bonora , C. P. Constantinidis , C. S. Xiong

Single-cell electrophysiological recordings provide a powerful window into neuronal functional diversity and offer an interpretable route for linking intrinsic physiology to transcriptomic identity. Here, we replicate and extend the…

Machine Learning · Computer Science 2026-03-12 Theo Schwider , Ramin Ramezani

Genetic interaction can be defined as a deviation of the phenotypic quantitative effect of a double gene mutation from the effect predicted from single mutations using a simple (e.g., multiplicative or linear additive) statistical model.…

Molecular Networks · Quantitative Biology 2015-04-24 Laurence Calzone , Emmanuel Barillot , Andrei Zinovyev

Defining the extent of epistasis - the non-independence of the effects of mutations - is essential for understanding the relationship of genotype, phenotype, and fitness in biological systems. The applications cover many areas of biological…

Quantitative Methods · Quantitative Biology 2016-07-06 Frank J. Poelwijk , Vinod Krishna , Rama Ranganathan

The electrocardiogram (ECG) records electrical signals in a non-invasive way to observe the condition of the heart, typically looking at the heart from 12 different directions. Several types of the cardiac disease are diagnosed by using…

Signal Processing · Electrical Eng. & Systems 2024-10-16 Yong-Yeon Jo , Young Sang Choi , Jong-Hwan Jang , Joon-Myoung Kwon

It is widely held that a substantial genetic component underlies Bipolar Disorder (BD) and other neuropsychiatric disease traits. Recent efforts have been aimed at understanding the genetic basis of disease susceptibility, with genome-wide…

The global burden of acute and chronic wounds presents a compelling case for enhancing wound classification methods, a vital step in diagnosing and determining optimal treatments. Recognizing this need, we introduce an innovative…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yash Patel , Tirth Shah , Mrinal Kanti Dhar , Taiyu Zhang , Jeffrey Niezgoda , Sandeep Gopalakrishnan , Zeyun Yu

This paper describes a Bayesian statistical method for determining the genetic basis of a complex genetic trait. The method uses a sample of unrelated individuals classified into two groups, for example cases and controls. Each group is…

Genomics · Quantitative Biology 2008-02-21 Toby Johnson

Electroencephalogram (EEG) classification plays a key role in medical diagnosis and brain-computer interfaces, but remains challenging due to low signal-to-noise ratios and high inter-subject variability. As a result, many existing…

Machine Learning · Computer Science 2026-05-18 Ahmad Bdeir , Johannes Burchert , Tom Hanika , Lars Schmidt-Thieme , Niels Landwehr

In order to describe two-dimensionally packed cells in epithelial tissues both mathematically and physically, there have been developed several sorts of geometrical models, such as the vertex model, the finite element model, the…

Biological Physics · Physics 2014-11-19 Yukitaka Ishimoto , Yoshihiro Morishita

Expression quantitative trait loci (eQTL) mapping aims to determine genomic regions that regulate gene transcription. Expression QTL is used to study the regulatory structure of normal tissues and to search for genetic factors in complex…

Genomics · Quantitative Biology 2011-05-31 Andrey A. Shabalin

We consider the Siegel modular variety of genus 2 and a p-integral model of it for a good prime p>2, which parametrizes principally polarized abelian varieties of dimension two with a level structure. We consider cycles on this model which…

alg-geom · Mathematics 2007-05-23 S. Kudla , M. Rapoport

We provide a classification of entangled states that uses new discrete entanglement invariants. The invariants are defined by algebraic properties of linear maps associated with the states. We prove a theorem on a correspondence between the…

Quantum Physics · Physics 2013-01-08 Roman V. Buniy , Thomas W. Kephart

Objective: A novel structure based on channel-wise attention mechanism is presented in this paper. Embedding with the proposed structure, an efficient classification model that accepts multi-lead electrocardiogram (ECG) as input is…

Signal Processing · Electrical Eng. & Systems 2020-03-27 Hao Tung , Chao Zheng , Xinsheng Mao , Dahong Qian

We systematically analyze the $d=5$ Weinberg operator at 2-loop order. Using a diagrammatic approach, we identify two different interesting categories of neutrino mass models: (i) Genuine 2-loop models for which both, tree-level and 1-loop…

High Energy Physics - Phenomenology · Physics 2015-03-26 D. Aristizabal Sierra , A. Degee , L. Dorame , M. Hirsch

Inside the moduli space of curves of genus three with one marked point, we consider the locus of hyperelliptic curves with a marked Weierstrass point, and the locus of non-hyperelliptic curves with a marked hyperflex. These loci have…

Algebraic Geometry · Mathematics 2016-02-26 Dawei Chen , Nicola Tarasca
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