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Biomolecular condensates are small droplets forming spontaneously in biological cells via phase separation. They play a role in many cellular processes, but it is unclear how cells control them. Cellular regulation often relies on…

Soft Condensed Matter · Physics 2024-03-15 Jan Kirschbaum , David Zwicker

The method developed by Michaelis and Menten was foundational in the development of our understanding of biochemical reaction kinetics. Extended models of metabolism encapsulated by reaction rate theory, stochastic reaction models, and…

Molecular Networks · Quantitative Biology 2024-01-11 Tjeerd V. olde Scheper

Current-induced magnetic switching of a single magnetic molecule attached to two ferromagnetic contacts is considered theoretically, with the main emphasis put on the role of intrinsic spin relaxation processes. It is shown that…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Maciej Misiorny , Józef Barnaś

We study the problem of controlling oscillations in closed loop by combining positive and negative feedback in a mixed configuration. We develop a complete design procedure to set the relative strength of the two feedback loops to achieve…

Systems and Control · Electrical Eng. & Systems 2021-09-08 W. Che , F. Forni

Motor proteins are active enzyme molecules that play a crucial role in many biological processes. They transform the chemical energy into the mechanical work and move unidirectionally along rigid cytoskeleton filaments. Single-molecule…

Soft Condensed Matter · Physics 2009-11-13 Rahul Kumar Das , Anatoly B. Kolomeisky

Increasing the enzyme concentration generally speeds up enzymatic reactions. However, in this Letter, we show that increasing the enzyme concentration can also slow down the enzymatic reaction. We consider a simple allosteric protein with…

Chemical Physics · Physics 2024-11-14 Tetsuhiro S. Hatakeyama

We consider a simple atomic two-body bound state system that is overall charge neutral and placed in a static electric and magnetic field, and calculate the magneto-electric response function as a function of frequency. This is done from…

Quantum Physics · Physics 2015-05-28 James Babington , Bart A. van Tiggelen

Naively, one expects the information communicated by an enzyme downstream within a signaling network, in which the enzyme is embedded, to grow monotonically with the enzyme's rate of product formation. However, here we observe that this…

Biological Physics · Physics 2020-07-01 Tushar Modi , S. Banu Ozkan , Steve Pressé

This work is devoted to the investigation of nontrivial transport properties in many-body quantum systems. Precisely, we study transport in the steady state of spin-1/2 Heisenberg XXZ chains, driven out of equilibrium by two magnetic baths…

Statistical Mechanics · Physics 2020-03-20 Alberto L. de Paula , Emmanuel Pereira , Raphael C. Drumond , M. C. O. Aguiar

Binding and unbinding of ligands to specific sites of a macromolecule are one of the most elementary molecular interactions inside the cell that embody the computational processes of biological regulations. The interaction between…

Molecular Networks · Quantitative Biology 2011-11-10 Hidenori Kimura , Hiroyuki Okano , Reiko J. Tanaka

A ubiquitous building block of signaling pathways is a cycle of covalent modification (e.g., phosphorylation and dephosphorylation in MAPK cascades). Our paper explores the kind of information processing and filtering that can be…

Molecular Networks · Quantitative Biology 2015-05-13 Carlos Gomez-Uribe , George C. Verghese , Leonid A. Mirny

Stochastic dynamics of chemical reactions in a mutually repressing two-gene circuit is numerically simulated. The circuit has a rich variety of different states when the kinetic change of DNA status is slow. The stochastic switching…

Disordered Systems and Neural Networks · Physics 2009-11-11 Tomohiro Ushikubo , Wataru Inoue , Mitsumasa Yoda , Masaki Sasai

Understanding the magnetization switching process in ferromagnetic thin films is essential for many technological applications. We investigate the effects of periodic driving via magnetic fields on a macrospin system under explicit…

Materials Science · Physics 2022-08-16 Michael Maihöfer , Johannes Reiff , Jörg Main , Rigoberto Hernandez

Energy dissipation is an unavoidable phenomenon of physical systems that are directly coupled to an external environmental bath. The ability to engineer the processes responsible for dissipation and coupling is fundamental to manipulate the…

Classical Physics · Physics 2017-06-28 Changyao Chen , Damián H. Zanette , David Czaplewski , Steven Shaw , Daniel López

We show that individual vibrational modes in single-molecule junctions with asymmetric molecule-lead coupling can be selectively excited by applying an external bias voltage. Thereby, a non-statistical distribution of vibrational energy can…

Mesoscale and Nanoscale Physics · Physics 2017-09-13 R. Volkovich , R. Härtle , M. Thoss , U. Peskin

Molecular motors convert chemical energy into mechanical work while operating in an environment dominated by Brownian motion. The aim of this paper is to explore the flow of energy between the molecular motors and its surroundings, in…

Statistical Mechanics · Physics 2011-05-06 Yunxin Zhang

The interaction of standard model's particles with the axionic Dark Matter field may generate oscillating nuclear electric dipole moments (EDMs), oscillating nuclear Schiff moments and oscillating nuclear magnetic quadrupole moments (MQMs)…

High Energy Physics - Phenomenology · Physics 2020-04-29 V. V. Flambaum , H. B. Tran Tan , D. Budker , A. Wickenbrock

We investigate the use of external time-dependent magnetic field for the control of the quantum states in a two-electron quantum ring. The hyperfine interaction of the confined electrons with surrounding nuclei couples the singlet state…

Mesoscale and Nanoscale Physics · Physics 2010-05-20 Jani Särkkä , Ari Harju

The de Haas - van Alphen effect in quasi-two-dimensional metals is studied at arbitrary parameters. The oscillations of the chemical potential may substantially change the temperature dependence of harmonic amplitudes that is usually used…

Statistical Mechanics · Physics 2009-11-07 Pavel Grigoriev

We demonstrate a method for controlling the outcome of an ultracold chemical few-body reaction by redirecting a tunable fraction of reaction flux from one selected product channel to another one. In the reaction, three ultracold atoms…