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We present a generic mechanism by which reproducing microorganisms, with a diffusivity that depends on the local population density, can form stable patterns. It is known that a decrease of swimming speed with density can promote separation…

Populations and Evolution · Quantitative Biology 2010-07-13 M. E. Cates , D. Marenduzzo , I. Pagonabarraga , J. Tailleur

The transition from a microscopic model for the movement of many particles to a macroscopic continuum model for a density flow is studied. The microscopic model for the free flow is completely deterministic, described by an interaction…

Statistical Mechanics · Physics 2021-01-12 Jennifer Weissen , Simone Göttlich , Dieter Armbruster

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

Populations and Evolution · Quantitative Biology 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

Gene networks exhibiting oscillatory dynamics are widespread in biology. The minimal regulatory designs giving rise to oscillations have been implemented synthetically and studied by mathematical modeling. However, most of the available…

Molecular Networks · Quantitative Biology 2013-01-31 Matteo Osella , Marco Cosentino Lagomarsino

Various bacterial strains exhibit colonial branching patterns during growth on poor substrates. These patterns reflect bacterial cooperative self-organization and cybernetic processes of communication, regulation and control employed during…

Condensed Matter · Physics 2015-06-25 Ido Golding , Yonathan Kozlovsky , Inon Cohen , Eshel Ben-Jacob

The bacterial flagellar motor plays a crucial role in both bacterial locomotion and chemotaxis. Recent experiments reveal that the switching dynamics of the motor depends on the motor rotation speed, and thus the motor torque,…

Biological Physics · Physics 2013-07-26 Fan Bai , Tohru Minamino , Zhanghan Wu , Keiichi Namba , Jianhua Xing

We study the chemotaxis of a population of genetically identical swimming bacteria undergoing run and tumble dynamics driven by stochastic switching between clockwise and counterclockwise rotation of the flagellar rotary system.…

Cell Behavior · Quantitative Biology 2020-07-17 Margaritis Voliotis , Jerko Rosko , Teuta Pilizota , Tanniemola Liverpool

The large-scale collective behavior of biological systems can be characterized by macroscopic transport, which arises from the non-equilibrium microscopic interactions among individual constituents. A prominent example is the formation of…

Statistical Mechanics · Physics 2025-07-29 Subhadip Chakraborti , Vasily Zaburdaev

Growth in bacterial populations generally depends on the environment (availability and quality of nutrients, presence of a toxic inhibitor, product inhibition..). Here, we build a model to describe the action of a bacteriostatic antibiotic,…

Biological Physics · Physics 2025-06-25 Barnabe Ledoux , David Lacoste

The physics of micron-scale biological colonies usually benefits from different out-of-equilibrium sources. In bacterial colonies and cellular tissues, the growth process is among the important active sources that determine the dynamics. In…

Soft Condensed Matter · Physics 2023-06-16 Forouh Maleki , Ali Najafi

We numerically examine a bidisperse system of active and passive particles coupled to a resource substrate. The active particles deplete the resource at a fixed rate and move toward regions with higher resources, while all of the particles…

Soft Condensed Matter · Physics 2024-04-23 L. Varga , A. Libal , C. Reichhardt , C. J. O. Reichhardt

Various bacterial strains (e.g. strains belonging to the genera Bacillus, Paenibacillus, Serratia and Salmonella) exhibit colonial branching patterns during growth on poor semi-solid substrates. These patterns reflect the bacterial…

Condensed Matter · Physics 2009-10-31 Yonathan Kozlovsky , Inon Cohen , Ido Golding , Eshel Ben-Jacob

Understanding how antibiotics inhibit bacteria can help to reduce antibiotic use and hence avoid antimicrobial resistance - yet few theoretical models exist for bacterial growth inhibition by a clinically relevant antibiotic treatment…

Cell Behavior · Quantitative Biology 2017-12-06 Philip Greulich , Jakub Dolezal , Matthew Scott , Martin R. Evans , Rosalind J. Allen

Density-dependent diffusion is a widespread phenomenon in nature. We have examined the density-dependent diffusion behavior of some biological processes such as tumor growth and invasion [23]. Here, we extend our previous work by developing…

Statistical Mechanics · Physics 2022-02-14 Ahmed M. Fouad , Marwa M. Fouad

In this paper, we consider a flocculation model in a chemostat where one species is present in two forms: planktonic and aggregated bacteria with the presence of a single resource. The removal rates of isolated and attached bacteria are…

Dynamical Systems · Mathematics 2023-12-08 Radhouane Fekih-Salem , Tewfik Sari

This paper theoretically analyzes a phenomenological stochastic model for bacterial growth. This model comprises cell division and the linear growth of cells, where growth rates and cell cycles are drawn from lognormal distributions. We…

Biological Physics · Physics 2016-06-28 Ken Yamamoto , Jun-ichi Wakita

We introduce a general theoretical framework to study the shape dynamics of actively growing and remodeling surfaces. Using this framework we develop a physical model for growing bacterial cell walls and study the interplay of cell shape…

Biological Physics · Physics 2016-04-08 Shiladitya Banerjee , Norbert F. Scherer , Aaron R. Dinner

Segregation of populations is a key question in evolution theory. One important aspect is the relation between spatial organization and the population's composition. Here we study a specific example -- sectors in expanding bacterial…

Condensed Matter · Physics 2009-10-31 Ido Golding , Inon Cohen , Eshel Ben-Jacob

A system of impulsive differential equations with state-dependent impulses is used to model the growth of a single population on two limiting essential resources in a self-cycling fermentor. Potential applications include water purification…

Dynamical Systems · Mathematics 2018-09-10 Ting-Hao Hsu , Tyler Meadows , Lin Wang , Gail S. K. Wolkowicz

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson