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We implemented a coarse-graining procedure to construct mesoscopic models of complex molecules. The final aim is to obtain better results on properties depending on slow modes of the molecules. Therefore the number of particles considered…

Soft Condensed Matter · Physics 2009-10-31 Hendrik Meyer , Oliver Biermann , Roland Faller , Dirk Reith , Florian Mueller-Plathe

Animals are known to make efficient probabilistic inferences based on uncertain and noisy information from the outside world. Although it is known that generic neural networks can perform near-optimal point estimation by probabilistic…

Neurons and Cognition · Quantitative Biology 2021-11-10 Kohei Ichikawa , Asaki Kataoka

The development of mechanistic models of biological systems is a central part of Systems Biology. One major task in developing these models is the inference of the correct model parameters. Due to the size of most realistic models and their…

Quantitative Methods · Quantitative Biology 2016-06-28 Jan Mikelson , Mustafa Khammash

Microalgae counting is used to measure biomass quantity. Usually, it is performed in a manual way using a Neubauer chamber and expert criterion, with the risk of a high error rate. This paper addresses the methodology for automatic…

Spectral molecular imaging is a new imaging technique able to discriminate and quantify different components of tissue simultaneously at high spatial and high energy resolution. Our MARS scanner is an x-ray based small animal CT system…

Process modeling and understanding are fundamental for advanced human-computer interfaces and automation systems. Most recent research has focused on activity recognition, but little has been done on sensor-based detection of process…

Inertial sensors based on micro-electromechanical systems (MEMS) technology, such as accelerometers and angular rate sensors, are cost-effective solutions used in inertial navigation systems in a broad spectrum of applications that estimate…

Robotics · Computer Science 2020-12-09 Hussein Al-Jlailaty , Mohammad M. Mansour

This study explores the deployment of three machine learning (ML) approaches for real-time prediction of glucose, lactate, and ammonium concentrations in cell culture processes, using Raman spectroscopy as input features. The research…

Quantitative Methods · Quantitative Biology 2025-09-04 Thanh Tung Khuat , Johnny Peng , Robert Bassett , Ellen Otte , Bogdan Gabrys

The proper biological functioning of proteins often relies on the occurrence of coordinated fluctuations around their native structure, or of wider and sometimes highly elaborated motions. Coarse-grained elastic-network descriptions are…

Biomolecules · Quantitative Biology 2013-10-17 Yves Dehouck , Alexander S. Mikhailov

This paper describes ANN-Benchmarks, a tool for evaluating the performance of in-memory approximate nearest neighbor algorithms. It provides a standard interface for measuring the performance and quality achieved by nearest neighbor…

Information Retrieval · Computer Science 2018-07-19 Martin Aumüller , Erik Bernhardsson , Alexander Faithfull

We propose an algorithm for molecular dynamics or Monte Carlo simulations that uses an interpolation procedure to estimate potential energy values from energies and gradients evaluated previously at points of a simplicial mesh. We chose an…

Computational Physics · Physics 2020-01-07 Konstantin Karandashev , Jiri Vanicek

Proposed here is a dynamic Monte-Carlo algorithm that is efficient in simulating dense systems of long flexible chain molecules. It expands on the configurational-bias Monte-Carlo method through the simultaneous generation of a large set of…

Statistical Mechanics · Physics 2018-08-29 Niels Boon

Accurate low dimension chemical kinetic models for methane are an essential component in the design of efficient gas turbine combustors. Kinetic models coupled to computational fluid dynamics (CFD) provide quick and efficient ways to test…

Chemical Physics · Physics 2022-06-10 Mark Kelly , Gilles Bourque , Stephen Dooley

Protein structure prediction is a critical problem linked to drug design, mutation detection, and protein synthesis, among other applications. To this end, evolutionary data has been used to build contact maps which are traditionally…

Biomolecules · Quantitative Biology 2022-11-08 Lakshmi A. Ghantasala , Risi Jaiswal , Supriyo Datta

The paper introduces a real-time monitoring and forecasting system for ecological phenomena. The process yields a collection of ecological parameters viewed as distributed time series, which are measured by means of wireless network of…

Computers and Society · Computer Science 2017-03-22 Janetta Culita , Alexandru Dumitrascu , Dan Stefanoiu

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Methodology · Statistics 2022-03-04 Kiheiji Nishida

In recent work we have presented a novel algorithm for mesh refinement which utilizes a reduced model. In particular, the reduced model is used to monitor the transfer of activity (e.g. mass, energy) from larger to smaller scales. When the…

Numerical Analysis · Mathematics 2014-02-27 Panagiotis Stinis

In this work we propose a novel algorithmic strategy that allows for an efficient characterization of the whole set of stable fluxes compatible with the metabolic constraints. The algorithm, based on the well-known Bethe approximation,…

Disordered Systems and Neural Networks · Physics 2010-04-02 Alfredo Braunstein , Roberto Mulet , Andrea Pagnani

Present study is dedicated to the problem of electrochemical analysis of multicomponent mixtures such as milk. A combination of cyclic voltammetry facilities and machine learning technique made it possible to create a pattern recognition…

Computational protein structure determination involves optimization in a problem space much too large to exhaustively search. Existing approaches include optimization algorithms such as gradient descent and simulated annealing, but these…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-04 Michael Bryson , Xijiang Miao , Homayoun Valafar