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Constraint-based optimization of microbial strains and model-based bioprocess design have been used extensively to enhance yields in biotechnological processes. However, strain and process optimization are usually carried out in sequential…

Optimization and Control · Mathematics 2024-07-31 Anita L. Ziegler , Ashutosh Manchanda , Marc-Daniel Stumm , Lars M. Blank , Alexander Mitsos

Bacterial sensor systems can be used for the detection and measurement of molecular signal concentrations. The dynamics of the sensor directly depend on the biological properties of the bacterial sensor cells; manipulation of these features…

Molecular Networks · Quantitative Biology 2024-06-26 Florian Anderl , Gabriela Salvadori , Mladen Veletic , Fernanda Cristina Petersen , Ilangko Balasingham

Here we design, construct, and characterize a compact Raman-spectroscopy-based sensor that measures the concentration of a water-methanol mixture. The sensor measures the concentration with an accuracy of 0.5% and a precision of 0.2% with a…

Instrumentation and Detectors · Physics 2018-08-16 Daniel D. Hickstein , Russell Goldfarmmuren , Jack Darrah , Luke Erickson , Laura A. Johnson

This article presents new hexagonal and pentagonal PEM fuel cell models. The models have been optimized after achieving improved cell performance. The input parameters of the multi-objective optimization algorithm were pressure and…

Neural and Evolutionary Computing · Computer Science 2023-10-18 Ali Jabbary , Nader Pourmahmoud , Mir Ali Asghar Abdollahi , Marc A. Rosen

Reliable identification of high-value products such as whisky is an increasingly important area, as issues such as brand substitution (i.e. fraudulent products) and quality control are critical to the industry. We have examined a range of…

An artificial neural network (ANN) is investigated as a tool for estimating rate coefficients for the collisional excitation of molecules. The performance of such a tool can be evaluated by testing it on a dataset of collisionally-induced…

Instrumentation and Methods for Astrophysics · Physics 2014-11-20 David A. Neufeld

We investigate the potential of numerical algorithms to decipher the kinetic parameters involved in multi-step chemical reactions. To this end we study a dimerization kinetics of protein as a model system. We follow the dimerization…

Biological Physics · Physics 2014-12-24 Srijeeta Talukder , Shrabani Sen , Ralf Metzler , Suman K Banik , Pinaki Chaudhury

Side-by-side comparison of detailed kinetic models using a new tool to aid recognition of species structures reveals significant discrepancies in the published rates of many reactions and thermochemistry of many species. We present a first…

Chemical Physics · Physics 2017-12-27 Sai Krishna Sirumalla , Morgan A. Mayer , Kyle E. Niemeyer , Richard H. West

Distillation is a unit operation with multiple input parameters and multiple output parameters. It is characterized by multiple variables, coupling between input parameters, and non-linear relationship with output parameters. Therefore, it…

Chemical Physics · Physics 2021-07-30 Chunli Li , Chunyu Wang

We present a machine learning based approach for real-time monitoring of particle detectors. The proposed strategy evaluates the compatibility between incoming batches of experimental data and a reference sample representing the data…

High Energy Physics - Experiment · Physics 2023-03-13 Gaia Grosso , Nicolò Lai , Marco Letizia , Jacopo Pazzini , Marco Rando , Andrea Wulzer , Marco Zanetti

This paper introduces a new method that combines Artificial Intelligence (AI) and quantum-inspired techniques to improve the efficiency of multi-variable optimization experiments. By using advanced software simulations, this approach…

The methanol molecule is a sensitive probe of astrochemistry, astrophysics, and fundamental physics. The first-principles elucidation and prediction of its rotation-torsional-vibrational motions are enabled in this work by the computation…

Chemical Physics · Physics 2025-08-05 Ayaki Sunaga , Tibor Győri , Gábor Czakó , Edit Matyus

Redox potentials of electron transfer reactions are of fundamental importance for the performance and description of electrochemical devices. Despite decades of research, accurate computational predictions for the redox potential of even…

Chemical Physics · Physics 2024-03-26 Ryosuke Jinnouchi , Ferenc Karsai , Georg Kresse

When directly coupled with fluctuating energy sources such as wind and photovoltage power, the alkaline electrolysis (AEL) in a power-to-hydrogen (P2H) system is required to operate flexibly by dynamically adjusting its hydrogen production…

Systems and Control · Electrical Eng. & Systems 2022-03-09 Xiaoyan Qiu , Hang Zhang , Yiwei Qiu , Buxiang Zhou , Tianlei Zang , Ruomei Qi , Jin Lin , Jiepeng Wang

Plant diseases are major causes of production losses and may have a significant impact on the agricultural sector. Detecting pests as early as possible can help increase crop yields and production efficiency. Several robotic monitoring…

Robotics · Computer Science 2023-08-29 Adi Yehoshua , Yael Edan

A local-sensitivity-analysis technique is employed to generate new skeletal reaction models for methane combustion from the foundational fuel chemistry model (FFCM-1). The sensitivities of the thermo-chemical variables with respect to the…

Chemical Physics · Physics 2023-08-30 Yinmin Liu , Hessam Babaee , Peyman Givi , Harsha Chelliah , Daniel Livescu , Arash Nouri

Efficient computational methods that are capable of supporting experimental measures obtained at constant values of pH and redox potential are important tools as they serve to, among other things, provide additional atomic level information…

Chemical Physics · Physics 2018-09-21 Vinícius Wilian D. Cruzeiro , Adrian E. Roitberg

In molecular dynamics (MD) simulation, force field determines the capability of an individual model in capturing physical and chemistry properties. The method for generating proper parameters of the force field form is the key component for…

Atomic and Molecular Clusters · Physics 2016-07-19 Ying Li , Hui Li , Maria K. Y. Chan , Subramanian Sankaranarayanan , Benoît Rouxb

Molecular dynamics simulations have become essential in many areas of atomistic modelling from drug discovery to materials science. They provide critical atomic-level insights into key dynamical events experiments cannot easily capture.…

Biological Physics · Physics 2024-06-14 Tiejun Wei , Balint Dudas , Edina Rosta

The production process involved in the creation of biofuels consists of a number of operations and steps that require a meticulous understanding of the parameters and metrics. The production techniques again differ depending on the…

Other Quantitative Biology · Quantitative Biology 2023-08-03 Amardeep Singh