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The classical approach to protein folding inspired by statistical mechanics avoids the high dimensional structure of the conformation space by using effective coordinates. Here we introduce a network approach to capture the statistical…

Biomolecules · Quantitative Biology 2007-05-23 Erzsebet Ravasz , S. Gnanakaran , Zoltan Toroczkai

We study the evolution of the network properties of a populated network embedded in a genotype space characterised by either a low or a high number of potential links, with particular emphasis on the connectivity and clustering. Evolution…

Statistical Mechanics · Physics 2007-05-23 Paul Anderson , Henrik Jeldtoft Jensen

The relationship between network topology and system dynamics has significant implications for unifying our understanding of the interplay among metabolic, gene-regulatory, and ecosystem network architecures. Here we analyze the stability…

Populations and Evolution · Quantitative Biology 2015-06-17 Cameron Smith , Raymond S. Puzio , Aviv Bergman

Inspired by empirical studies of networked systems such as the Internet, social networks, and biological networks, researchers have in recent years developed a variety of techniques and models to help us understand or predict the behavior…

Statistical Mechanics · Physics 2015-06-24 M. E. J. Newman

In this paper we present a network model to study the impact of spatial distribution of constituents, coupling between them and diffusive processes in the context of biological situations. The model is in terms of network of mobile elements…

Molecular Networks · Quantitative Biology 2007-05-23 Kanchan Thadani , Ashutosh

The human organism is an integrated network where complex physiologic systems, each with its own regulatory mechanisms, continuously interact, and where failure of one system can trigger a breakdown of the entire network. Identifying and…

Data Analysis, Statistics and Probability · Physics 2012-03-02 Amir Bashan , Ronny P. Bartsch , Jan W. Kantelhardt , Shlomo Havlin , Plamen Ch. Ivanov

Many methods have been developed for finding the commonalities between different organisms to study their phylogeny. The structure of metabolic networks also reveal valuable insights into metabolic capacity of species as well as into the…

Molecular Networks · Quantitative Biology 2016-04-08 Krishanu Deyasi , Anirban Banerjee , Bony Deb

Networks are useful for describing systems of interacting objects, where the nodes represent the objects and the edges represent the interactions between them. The applications include chemical and metabolic systems, food webs as well as…

Computational Physics · Physics 2009-10-20 Baruch Barzel , Ofer Biham

Paths are important structural elements in complex networks because they are finite (unlike walks), related to effective node coverage (minimum spanning trees), and can be understood as being dual to star connectivity. This article…

Physics and Society · Physics 2007-12-05 Luciano da Fontoura Costa

We have generalized our ``unified'' model of evolutionary ecology by taking into account the possible movements of the organisms from one ``patch'' to another within the same eco-system. We model the spatial extension of the eco-system…

Populations and Evolution · Quantitative Biology 2009-11-10 Dietrich Stauffer , Ambarish Kunwar , Debashish Chowdhury

Many foraging microorganisms rely upon cellular transport networks to deliver nutrients, fluid and organelles between different parts of the organism. Networked organisms ranging from filamentous fungi to slime molds demonstrate a…

Adaptation and Self-Organizing Systems · Physics 2020-12-08 Cassidy Mentus , Marcus Roper

Human social networks are inherently multiplex, comprising overlapping layers of relationships. Different layers may have distinct structural properties and interpersonal dynamics, but also may interact to form complex interdependent…

Social and Information Networks · Computer Science 2025-10-22 Yongren Shi , Edo Airoldi , Nicholas A. Christakis

The structure of ecological networks, in particular food webs, determines their ability to evolve further, i.e. evolvability. The knowledge about how food web evolvability is determined by the structures of diverse ecological networks can…

Populations and Evolution · Quantitative Biology 2015-07-13 Jianxi Luo

Network ecology is a rising field of quantitative biology representing ecosystems as complex networks. A suitable example is parasite spreading: several parasites may be transmitted among their hosts through different mechanisms, each one…

Quantitative Methods · Quantitative Biology 2016-09-12 Massimo Stella , Cecilia S. Andreazzi , Sanja Selakovic , Alireza Goudarzi , Alberto Antonioni

The propagations of diseases, behaviors and information in real systems are rarely independent of each other, but they are coevolving with strong interactions. To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and…

Physics and Society · Physics 2019-10-02 Wei Wang , Quan-Hui Liu , Junhao Liang , Yanqing Hu , Tao Zhou

The stability of ecosystems as well as the relation between topology and dynamics on multilayer networks are important questions that are usually discussed in separate communities. Here, we combine these two topics by investigating the…

Populations and Evolution · Quantitative Biology 2015-07-24 Jonas Richhardt , Sebastian Plitzko , Florian Schwarzmüller , Barbara Drossel

Understanding how and how far information, behaviors, or pathogens spread in social networks is an important problem, having implications for both predicting the size of epidemics, as well as for planning effective interventions. There are,…

Physics and Society · Physics 2015-05-28 Jukka-Pekka Onnela , Nicholas A. Christakis

Many real-world networks, ranging from subway systems to polymer structures and fungal mycelia, do not form by the incremental addition of individual nodes but instead grow through the successive extension and intersection of lines or…

Physics and Society · Physics 2026-01-14 Marc Barthelemy

Spatially or chemically isolated functional modules composed of several cellular components and carrying discrete functions are considered fundamental building blocks of cellular organization, but their presence in highly integrated…

Soft Condensed Matter · Physics 2009-11-07 E. Ravasz , A. L. Somera , D. A. Mongru , Z. N. Oltvai , A. -L. Barabasi

A growing set of applications consider the process of network formation by using subgraphs as a tool for generating the network topology. One of the pressing research challenges is thus to be able to use these subgraphs to understand the…

Social and Information Networks · Computer Science 2019-04-11 Soumajyoti Sarkar , Hamidreza Alvari , Paulo Shakarian