Related papers: Unbalanced synaptic inhibition can create intensit…
A mathematical model describing the coupling between two independent amplification mechanisms in auditory hair cells is proposed and analyzed. Hair cells are cells in the inner ear responsible for translating sound-induced mechanical…
Oscillators coupled in a network can synchronize with each other to yield a coherent population rhythm. If multiple such networks are coupled together, the question arises whether these rhythms will synchronize. We investigate the impact of…
Past work has reported inverted-U relationships between arousal and auditory task performance, but the underlying neural network mechanisms remain unclear. To make progress, we recorded auditory cortex activity from behaving mice during…
It is widely appreciated that well-balanced excitation and inhibition are necessary for proper function in neural networks. However, in principle, such balance could be achieved by many possible configurations of excitatory and inhibitory…
Neurons in the intact brain receive a continuous and irregular synaptic bombardment from excitatory and inhibitory pre-synaptic neurons, which determines the firing activity of the stimulated neuron. In order to investigate the influence of…
A great deal of research has been devoted on the investigation of neural dynamics in various network topologies. However, only a few studies have focused on the influence of autapses, synapses from a neuron onto itself via closed loops, on…
The sensory-triggered activity of a neuron is typically characterized in terms of a tuning curve, which describes the neuron's average response as a function of a parameter that characterizes a physical stimulus. What determines the shapes…
The study of balanced networks of excitatory and inhibitory neurons has led to several open questions. On the one hand it is yet unclear whether the asynchronous state observed in the brain is autonomously generated, or if it results from…
The human sense of hearing perceives a combination of sounds 'in tune' if the corresponding harmonic spectra are correlated, meaning that the neuronal excitation pattern in the inner ear exhibits some kind of order. Based on this…
We show that for two identical neuronal oscillators with strictly positive phase resetting curve, isochronous synchrony is an unstable attractor and arbitrarily weak noise can destroy entrainment and generate intermittent phase slips. Small…
Fast-spiking (FS) interneurons in the brain are self-innervated by powerful inhibitory GABAergic autaptic connections. By computational modelling, we investigate how autaptic inhibition regulates the firing response of such interneurons.…
The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons…
Noise appears in the brain due to various sources, such as ionic channel fluctuations and synaptic events. They affect the activities of the brain and influence neuron action potentials. Stochastic differential equations have been used to…
Artificial neural networks normally require precise weights to operate, despite their origins in biological systems, which can be highly variable and noisy. When implementing artificial networks which utilize analog 'synaptic' devices to…
A perturbative method is developed for calculating the effects of recurrent synaptic interactions between neurons embedded in a network. A series expansion is constructed that converges for networks with noisy membrane potential and weak…
We investigate the possibility that narrowband oscillations may emerge from completely asynchronous, independent neural firing. We find that a population of asynchronous neurons may produce narrowband oscillations if each neuron fires…
For a system of type-I neurons bidirectionally coupled through a nonlinear feedback mechanism, we discuss the issue of noise-induced complete synchronization (CS). For the inputs to the neurons, we point out that the rate of change of…
We study the noise activated dynamics of a model {\it autapse} neuron system that consists of a subcritical Hopf oscillator with a time delayed nonlinear feedback. The coherence of the noise driven pulses of the neuron exhibits a novel…
Large networks of sparsely coupled, excitatory and inhibitory cells occur throughout the brain. A striking feature of these networks is that they are chaotic. How does this chaos manifest in the neural code? Specifically, how variable are…
Neurons are subject to various kinds of noise. In addition to synaptic noise, the stochastic opening and closing of ion channels represents an intrinsic source of noise that affects the signal processing properties of the neuron. In this…