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In the present study we have used a set of methods and metrics to build a graph of relative neural connections in a hippocampus of a rodent. A set of graphs was built on top of time-sequenced data and analyzed in terms of dynamics of a…

Neurons and Cognition · Quantitative Biology 2023-08-08 Konstantin Sorokin , Andrey Zaitsew , Aleksandr Levin , German Magai , Maxim Beketov , Vladimir Sotskov

Hippocampal place and time cells encode spatial and temporal aspects of experience. Both have the same neural substrate, but have been modeled as having different functions and mechanistic origins, place cells as continuous attractors, and…

Neurons and Cognition · Quantitative Biology 2026-04-02 Qiaorong S. Yu , Zhaoze Wang , Vijay Balasubramanian

A hallmark of human intelligence is the ability to adapt to new situations, by applying learned rules to new content (systematicity) and thereby enabling an open-ended number of inferences and actions (generativity). Here, we propose that…

Neurons and Cognition · Quantitative Biology 2021-08-10 Randall C. O'Reilly , Charan Ranganath , Jacob L. Russin

A given neural network in the brain is involved in many different tasks. This implies that, when considering a specific task, the network's connectivity contains a component which is related to the task and another component which can be…

Neurons and Cognition · Quantitative Biology 2021-03-17 Friedrich Schuessler , Alexis Dubreuil , Francesca Mastrogiuseppe , Srdjan Ostojic , Omri Barak

Cross-correlations in the activity in neural networks are commonly used to characterize their dynamical states and their anatomical and functional organizations. Yet, how these latter network features affect the spatiotemporal structure of…

Neurons and Cognition · Quantitative Biology 2018-09-26 Ran Darshan , Carl van Vreeswijk , David Hansel

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

Neurons and Cognition · Quantitative Biology 2015-10-28 Shi Gu , Fabio Pasqualetti , Matthew Cieslak , Scott T. Grafton , Danielle S. Bassett

Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…

Neurons and Cognition · Quantitative Biology 2020-01-20 Nicola Pedreschi , Christophe Bernard , Wesley Clawson , Pascale Quilichini , Alain Barrat , Demian Battaglia

A mechanism for self-organization of the degree of connectivity in model neural networks is studied. Network connectivity is regulated locally on the basis of an order parameter of the global dynamics which is estimated from an observable…

Statistical Mechanics · Physics 2009-11-07 Stefan Bornholdt , Torsten Roehl

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

A computer model is described which is used to assess the dynamical complexity of a class of networks of spiking neurons with small-world properties. Networks are constructed by forming an initially segregated set of highly intra-connected…

Biological Physics · Physics 2009-11-13 Murray Shanahan

Understanding how brain networks learn and manage multiple tasks simultaneously is of interest in both neuroscience and artificial intelligence. In this regard, a recent research thread in theoretical neuroscience has focused on how…

Neurons and Cognition · Quantitative Biology 2024-08-05 Giacomo Vedovati , ShiNung Ching

Complex systems in the real world can be modeled as a network of connected components. The human brain, as a network of neurons among which the interactions cause perception, is a complex network. Synchronization is a dynamical phenomenon…

Biological Physics · Physics 2019-04-30 Arefeh Mazarei , Mohammad Amirian Matlob , Gholamhossein Riazi , Yousef Jamali

One of the paramount challenges in neuroscience is to understand the dynamics of individual neurons and how they give rise to network dynamics when interconnected. Historically, researchers have resorted to graph theory, statistics, and…

Neurons and Cognition · Quantitative Biology 2019-02-08 Jean-Baptiste Bardin , Gard Spreemann , Kathryn Hess

The dynamical responses of complex neuronal networks to external stimulus injected on a \emph{single} neuron are investigated. Stimulating the largest-degree neuron in the network, it is found that as the intensity of the stimulus…

Chaotic Dynamics · Physics 2016-04-13 Mengjiao Chen , Weijie Lin , Hengtong Wang , Wei Ren , Xingang Wang

Studies of the dynamics of nonlinear recurrent neural networks often assume independent and identically distributed couplings, but large-scale connectomics data indicate that biological neural circuits exhibit markedly different…

Neurons and Cognition · Quantitative Biology 2025-10-28 David G. Clark , Owen Marschall , Alexander van Meegen , Ashok Litwin-Kumar

Degeneration and adaptation are two competing sides of the same coin called resilience in the progressive processes of brain aging or diseases. Degeneration accumulates during brain aging and other cerebral activities, causing structural…

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

We are offering a particular interpretation (well within the range of experimentally and theoretically accepted notions) of neural connectivity and dynamics and discuss it as the data-and-process architecture of the visual system. In this…

Neurons and Cognition · Quantitative Biology 2014-07-08 Christoph von der Malsburg

Networks are universally considered as complex structures of interactions of large multi-component systems. In order to determine the role that each node has inside a complex network, several centrality measures have been developed. Such…

Physics and Society · Physics 2019-08-20 Malbor Asllani , Bruno Requiao da Cunha , Ernesto Estrada , James P. Gleeson

Objective. Long-term potentiation (LTP) is a fundamental mechanism underlying learning and memory, yet its investigation at the network level in vitro remains challenging, particularly when optogenetic stimulation is used. The objective of…

Biological Physics · Physics 2026-02-13 Matteo Dominici , Ilya Auslender , Clara Zaccaria , Yasaman Heydari , Lorenzo Pavesi
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