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The spatiotemporal patterns of neural dynamics are jointly shaped by directed structural interactions and heterogeneous intrinsic features of the neural components. Despite well-developed methods for estimating directionality in network…

Neurons and Cognition · Quantitative Biology 2025-10-07 Jiawen Chang , Zhuda Yang , Changsong Zhou

During sleep, the hippocampus recapitulates neuronal patterns corresponding to behavioral trajectories during previous experiences. This hippocampal replay supports the formation of long-term memories. Yet, whether replay originates within…

Neurons and Cognition · Quantitative Biology 2022-05-06 Adrien Peyrache

Collective rhythmic dynamics from neurons is vital for cognitive functions such as memory formation but how neurons self-organize to produce such activity is not well understood. Attractor-based models have been successfully implemented as…

Neurons and Cognition · Quantitative Biology 2013-03-22 Mark Niedringhaus , Xin Chen , Katherine Conant , Rhonda Dzakpasu

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered…

Neurons and Cognition · Quantitative Biology 2009-12-14 Casey M. Schneider-Mizell , Jack M. Parent , Eshel Ben-Jacob , Michal Zochowski , Leonard M. Sander

The spiking activity of the hippocampal place cells plays a key role in producing and sustaining an internalized representation of the ambient space---a cognitive map. These cells do not only exhibit location-specific spiking during…

Neurons and Cognition · Quantitative Biology 2018-11-05 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…

Neurons and Cognition · Quantitative Biology 2021-06-04 Udaya B. Rongala , Henrik Jörntell

In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…

Neurons and Cognition · Quantitative Biology 2019-03-29 Peter Helfer , Thomas R. Shultz

In the mammalian brain, newly acquired memories depend on the hippocampus for maintenance and recall, but over time the neocortex takes over these functions, rendering memories hippocampus-independent. The process responsible for this…

Neurons and Cognition · Quantitative Biology 2021-07-02 Peter Helfer , Thomas R. Shultz

Many neural systems display cascading behavior characterized by uninterrupted sequences of neuronal firing. This gap precludes an understanding of how variations in network structure manifest in neural dynamics and either support or impinge…

Neurons and Cognition · Quantitative Biology 2019-11-12 Harang Ju , Jason Z. Kim , Danielle S. Bassett

Rich, spontaneous brain activity has been observed across a range of different temporal and spatial scales. These dynamics are thought to be important t for efficient neural functioning. Experimental evidence suggests that these neural…

Neurons and Cognition · Quantitative Biology 2015-01-21 Peter J. Hellyer , Barbara Jachs , Robert Leech , Claudia Clopath

Balanced neural networks -- in which excitatory and inhibitory inputs compensate each other on average -- give rise to a dynamical phase dominated by fluctuations called asynchronous state, crucial for brain functioning. However, structural…

Statistical Mechanics · Physics 2024-03-05 Jorge Pretel , Victor Buendía , Joaquín J. Torres , Miguel A. Muñoz

Recurrent neural networks are frequently studied in terms of their information-processing capabilities. The structural properties of these networks are seldom considered, beyond those emerging from the connectivity tuning necessary for…

Molecular Networks · Quantitative Biology 2025-02-20 Maria Sol Vidal-Saez , Jordi Garcia-Ojalvo

Neural circuits comprise multiple interconnected regions, each with complex dynamics. The interplay between local and global activity is thought to underlie computational flexibility, yet the structure of multiregion neural activity and its…

Neurons and Cognition · Quantitative Biology 2025-01-09 David G. Clark , Manuel Beiran

In this paper, we propose a new scheme for modelling the diverse behavior of neurons. We introduce the conditional activation, in which a neurons activation function is dynamically modified by a control signal. We apply this method to…

Neural and Evolutionary Computing · Computer Science 2018-03-15 Albert Lee , Bonnie Lam , Wenyuan Li , Hochul Lee , Wei-Hao Chen , Meng-Fan Chang , Kang. -L. Wang

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

Disordered Systems and Neural Networks · Physics 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

Can neural networks learn goal-directed behaviour using similar strategies to the brain, by combining the relationships between the current state of the organism and the consequences of future actions? Recent work has shown that recurrent…

Neurons and Cognition · Quantitative Biology 2021-01-21 Justin Jude , Matthias H. Hennig

This thesis is a compendium of research which brings together ideas from the fields of Complex Networks and Computational Neuroscience to address two questions regarding neural systems: 1) How the activity of neurons, via synaptic changes,…

Neurons and Cognition · Quantitative Biology 2013-02-19 Samuel Johnson

Several approaches to cognition and intelligence research rely on statistics-based models testing, namely factor analysis. In the present work we exploit the emerging dynamical systems perspective putting the focus on the role of the…

Physics and Society · Physics 2018-03-15 Gemma Rosell-Tarragó , Emanuele Cozzo , Albert Díaz-Guilera

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

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