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We study homomorphism polynomials, which are polynomials that enumerate all homomorphisms from a pattern graph $H$ to $n$-vertex graphs. These polynomials have received a lot of attention recently for their crucial role in several new…

Computational Complexity · Computer Science 2020-11-17 Balagopal Komarath , Anurag Pandey , C. S. Rahul

Signed networks, i.e., networks with positive and negative edges, commonly arise in various domains from social media to epidemiology. Modeling signed networks has many practical applications, including the creation of synthetic data sets…

Quantitative Methods · Quantitative Biology 2022-11-18 Angelina Brilliantova , Hannah Miller , Ivona Bezáková

Graph spectra are an important class of structural features on graphs that have shown promising results in enhancing Graph Neural Networks (GNNs). Despite their widespread practical use, the theoretical understanding of the power of…

Machine Learning · Computer Science 2025-03-04 Jingchu Gai , Yiheng Du , Bohang Zhang , Haggai Maron , Liwei Wang

Deep generative models have recently made a remarkable progress in capturing complex probability distributions over graphs. However, they are intractable and thus unable to answer even the most basic probabilistic inference queries without…

Machine Learning · Computer Science 2024-08-20 Milan Papež , Martin Rektoris , Václav Šmídl , Tomáš Pevný

Networks are often characterized by node heterogeneity for which nodes exhibit different degrees of interaction and link homophily for which nodes sharing common features tend to associate with each other. In this paper, we propose a new…

Methodology · Statistics 2018-03-13 Ting Yan , Binyan Jiang , Stephen E. Fienberg , Chenlei Leng

Treating neural network inputs and outputs as random variables, we characterize the structure of neural networks that can be used to model data that are invariant or equivariant under the action of a compact group. Much recent research has…

Machine Learning · Statistics 2020-09-18 Benjamin Bloem-Reddy , Yee Whye Teh

Genetic Regulatory Networks (GRNs) plays a vital role in the understanding of complex biological processes. Modeling GRNs is significantly important in order to reveal fundamental cellular processes, examine gene functions and understanding…

Computational Engineering, Finance, and Science · Computer Science 2012-05-10 Khalid Raza , Rafat Parveen

Gene regulatory network inference is crucial for understanding the complex molecular interactions in various genetic and environmental conditions. The rapid development of single-cell RNA sequencing (scRNA-seq) technologies unprecedentedly…

Methodology · Statistics 2021-11-09 Feiyi Xiao , Junjie Tang , Huaying Fang , Ruibin Xi

In areas such as computer software and hardware, manufacturing systems, and transportation, engineers encounter networks with arbitrarily large numbers of isomorphic subprocesses. Parameterized systems provide a framework for modeling such…

Formal Languages and Automata Theory · Computer Science 2016-10-03 M. H. Zibaeenejad , J. G. Thistle

Isoforms are mRNAs produced from the same gene site in the phenomenon called Alternative Splicing. Studies have shown that more than 95% of human multi-exon genes have undergone alternative splicing. Although there are few changes in mRNA…

Genomics · Quantitative Biology 2023-04-26 Sara Ghazanfari , Ali Rasteh , Seyed Abolfazl Motahari , Mahdieh Soleymani Baghshah

While all kinds of mixed data -from personal data, over panel and scientific data, to public and commercial data- are collected and stored, building probabilistic graphical models for these hybrid domains becomes more difficult. Users spend…

Machine Learning · Computer Science 2017-11-07 Alejandro Molina , Antonio Vergari , Nicola Di Mauro , Sriraam Natarajan , Floriana Esposito , Kristian Kersting

Hypernetworks are neural networks that generate weights for another neural network. We formulate the hypernetwork training objective as a compromise between accuracy and diversity, where the diversity takes into account trivial symmetry…

Machine Learning · Statistics 2018-04-10 Lior Deutsch

The need for consistent treatment of uncertainty has recently triggered increased interest in probabilistic deep learning methods. However, most current approaches have severe limitations when it comes to inference, since many of these…

Gene expression-based heterogeneity analysis has been extensively conducted. In recent studies, it has been shown that network-based analysis, which takes a system perspective and accommodates the interconnections among genes, can be more…

Methodology · Statistics 2023-08-09 Rong Li , Qingzhao Zhang , Shuangge Ma

Random graphs are more and more used for modeling real world networks such as evolutionary networks of proteins. For this purpose we look at two different models and analyze how properties like connectedness and degree distributions are…

Probability · Mathematics 2019-02-05 Klemens Taglieber , Uta Freiberg

Characterizing the structural properties of neural networks is crucial yet poorly understood, and there are no well-established similarity measures between networks. In this work, we observe that neural networks can be represented as…

Machine Learning · Computer Science 2021-06-01 David Pérez-Fernández , Asier Gutiérrez-Fandiño , Jordi Armengol-Estapé , Marta Villegas

Recently, increasing attention has been paid to heterogeneous graph representation learning (HGRL), which aims to embed rich structural and semantic information in heterogeneous information networks (HINs) into low-dimensional node…

Machine Learning · Computer Science 2022-10-12 Zhiqiang Zhong , Cheng-Te Li , Jun Pang

Neural networks (NN) have achieved state-of-the-art performance in various applications. Unfortunately in applications where training data is insufficient, they are often prone to overfitting. One effective way to alleviate this problem is…

Machine Learning · Computer Science 2016-11-03 Hao Wang , Xingjian Shi , Dit-Yan Yeung

The interdependence between nodes in graphs is key to improve class predictions on nodes and utilized in approaches like Label Propagation (LP) or in Graph Neural Networks (GNN). Nonetheless, uncertainty estimation for non-independent…

Machine Learning · Statistics 2021-10-28 Maximilian Stadler , Bertrand Charpentier , Simon Geisler , Daniel Zügner , Stephan Günnemann

Cellular differentiation is governed by gene regulatory networks, the high-dimensional stochastic biochemical systems that determine the transcriptional landscape and mediate cellular responses to signals and perturbations. Although…

Molecular Networks · Quantitative Biology 2026-04-29 Suryanarayana Maddu , Victor Chardès , Michael J. Shelley