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Background: The evolution of microRNA regulation in metazoans is a mysterious process: MicroRNA sequences are highly conserved among distal organisms, but on the other hand, there is no evident conservation of their targets. Results: We…
For random field theory based multiple comparison corrections In brain imaging, it is often necessary to compute the distribution of the supremum of a random field. Unfortunately, computing the distribution of the supremum of the random…
The effects of treatments may differ between persons with different characteristics. Addressing such treatment heterogeneity is crucial to investigate whether patients with specific characteristics are likely to benefit from a new…
Researchers are often interested in drawing inferences regarding the order between two experimental groups on the basis of multivariate response data. Since standard multivariate methods are designed for two-sided alternatives, they may not…
Consistently checking the statistical significance of experimental results is one of the mandatory methodological steps to address the so-called "reproducibility crisis" in deep reinforcement learning. In this tutorial paper, we explain how…
Machine learning algorithms permeate the day-to-day aspects of our lives and therefore studying the fairness of these algorithms before implementation is crucial. One way in which bias can manifest in a dataset is through missing values.…
Real-world classification problems typically exhibit an imbalanced or long-tailed label distribution, wherein many labels are associated with only a few samples. This poses a challenge for generalisation on such labels, and also makes…
Motivation: Human genomic datasets often contain sensitive information that limits use and sharing of the data. In particular, simple anonymisation strategies fail to provide sufficient level of protection for genomic data, because the data…
Algorithmic decision making process now affects many aspects of our lives. Standard tools for machine learning, such as classification and regression, are subject to the bias in data, and thus direct application of such off-the-shelf tools…
We present a loss function for neural networks that encompasses an idea of trivial versus non-trivial predictions, such that the network jointly determines its own prediction goals and learns to satisfy them. This permits the network to…
Domain adaptation aims to transfer the knowledge learned on (data-rich) source domains to (low-resource) target domains, and a popular method is invariant representation learning, which matches and aligns the data distributions on the…
Test case prioritisation (TCP) is a critical task in regression testing to ensure quality as software evolves. Machine learning has become a common way to achieve it. In particular, learning-to-rank (LTR) algorithms provide an effective…
Learning algorithms that learn linear models often have high representation bias on real-world problems. In this paper, we show that this representation bias can be greatly reduced by discretization. Discretization is a common procedure in…
We reproduced the results of CheXNet with fixed hyperparameters and 50 different random seeds to identify 14 finding in chest radiographs (x-rays). Because CheXNet fine-tunes a pre-trained DenseNet, the random seed affects the ordering of…
As large language models (LLMs) have grown in prevalence, particular benchmarks have become essential for the evaluation of these models and for understanding model capabilities. Most commonly, we use test accuracy averaged across multiple…
Can autoregressive large language models (LLMs) learn consistent probability distributions when trained on sequences in different token orders? We prove formally that for any well-defined probability distribution, sequence perplexity is…
In (exploratory) factor analysis, the loading matrix is identified only up to orthogonal rotation. For identifiability, one thus often takes the loading matrix to be lower triangular with positive diagonal entries. In Bayesian inference, a…
This study aims to understand how statistical biases affect the model's ability to generalize to in-distribution and out-of-distribution data on algorithmic tasks. Prior research indicates that transformers may inadvertently learn to rely…
Test data measured by medical instruments often carry imprecise ranges that include the true values. The latter are not obtainable in virtually all cases. Most learning algorithms, however, carry out arithmetical calculations that are…
The differences in distributional patterns between benchmark data and real-world data have been one of the main challenges of using electroencephalogram (EEG) signals for eye-tracking (ET) classification. Therefore, increasing the…