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The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation.…

Quantitative Methods · Quantitative Biology 2007-05-23 M. S. Barbosa , L. da F. Costa , E. S. Bernardes , G. Ramakers , J. van Pelt

Dendrites are branched neuronal processes that receive input signals from other neurons or the outside world [1]. To maintain connectivity as the organism grows, dendrites must also continue to grow. For example, the dendrites in the…

Neurons and Cognition · Quantitative Biology 2016-11-21 Sujoy Ganguly , Olivier Trottier , Xin Liang , Hugo Bowne-Anderson , Jonathon Howard

This paper describes how realistic neuromorphic networks can have their connectivity properties fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa

From the smallest biological systems to the largest cosmological structures, spatial domains undergo expansion and contraction. Within these growing domains, diffusive transport is a common phenomenon. Mathematical models have been widely…

Populations and Evolution · Quantitative Biology 2023-06-27 Stuart T. Johnston , Matthew J. Simpson

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu

The study of dynamical systems defined on complex networks provides a natural framework with which to investigate myriad features of neural dynamics, and has been widely undertaken. Typically, however, networks employed in theoretical…

Neurons and Cognition · Quantitative Biology 2013-02-22 Reuben O'Dea , Jonathan J. Crofts , Marcus Kaiser

Uncovering the mechanisms behind long-term memory is one of the most fascinating open problems in neuroscience and artificial intelligence. Artificial associative memory networks have been used to formalize important aspects of biological…

Machine Learning · Statistics 2023-11-20 Luca Ambrogioni

How far is neuroepithelial cell proliferation in the developing central nervous system a deterministic process? Or, to put it in a more precise way, how accurately can it be described by a deterministic mathematical model? To provide tracks…

Analysis of PDEs · Mathematics 2010-05-04 Jean Clairambault , Vladimir Flores , Benoit Perthame , Melina Rapacioli , Edmundo Rofman , Rafael Verdes

We develop methods for investigating protein drift-diffusion dynamics in heterogeneous cell membranes and the roles played by geometry, diffusion, chemical kinetics, and phase separation. Our hybrid stochastic numerical methods combine…

Biological Physics · Physics 2023-02-28 Patrick D. Tran , Thomas A. Blanpied , Paul J. Atzberger

Neuroscientific data analysis has classically involved methods for statistical signal and image processing, drawing on linear algebra and stochastic process theory. However, digitized neuroanatomical data sets containing labelled neurons,…

Computational Geometry · Computer Science 2018-05-15 Suyi Wang , Xu Li , Partha Mitra , Yusu Wang

We consider a model of aggregation, both diffusion-limited and ballistic, based on the Cayley tree. Growth is from the leaves of the tree towards the root, leading to non-trivial screening and branch competition effects. The model exhibits…

Soft Condensed Matter · Physics 2009-10-31 M. B. Hastings , Thomas C. Halsey

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

Neurons and Cognition · Quantitative Biology 2022-04-15 Sean Knight , Navjot Gadda

We suggest a modification of a comb model to describe anomalous transport in spiny dendrites. Geometry of the comb structure consisting of a one-dimensional backbone and lateral branches makes it possible to describe anomalous diffusion,…

Statistical Mechanics · Physics 2017-07-26 Vicenç Méndez , Alexander Iomin

The ongoing explosion of genome sequence data is transforming how we reconstruct and understand the histories of biological systems. Across biological scales, from individual cells to populations and species, trees-based models provide a…

Populations and Evolution · Quantitative Biology 2025-12-08 Yun Deng , Shing H. Zhan , Yulin Zhang , Chao Zhang , Bingjie Chen

Networks having the geometry and the connectivity of trees are considered as the spatial support of spatiotemporal dynamical processes. A tree is characterized by two parameters: its ramification and its depth. The local dynamics at the…

Pattern Formation and Solitons · Physics 2009-11-07 M. G. Cosenza , K. Tucci

Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these processes, but efforts have traditionally…

In this work, we answer an open problem in the study of phylogenetic networks. Phylogenetic trees are rooted binary trees in which all edges are directed away from the root, whereas phylogenetic networks are rooted acyclic digraphs. For the…

Populations and Evolution · Quantitative Biology 2015-11-12 Andreas D. M. Gunawan , Bhaskar DasGupta , Louxin Zhang

Denoising diffusion models have proven to be a flexible and effective paradigm for generative modelling. Their recent extension to infinite dimensional Euclidean spaces has allowed for the modelling of stochastic processes. However, many…

Brain networks exhibit remarkable structural properties, including high local clustering, short path lengths, and heavy-tailed weight and degree distributions. While these features are thought to enable efficient information processing with…

Biological Physics · Physics 2026-01-09 Aitor Morales-Gregorio , Anno C. Kurth , Karolína Korvasová

Given recipe of qualitative, kinetic modelling by geometric methods of three-dimensional dendritic crystals. Characteristic features of the perturbations appearing on the surface of a spherical body, leading to different scenarios of the…

Materials Science · Physics 2018-10-05 Alexander S. Prokhoda