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The effect of a high-frequency signal on the FitzHugh-Nagumo excitable model is analyzed. We show that the firing rate is diminished as the ratio of the high-frequency amplitude to its frequency is increased. Moreover, it is demonstrated…

Statistical Mechanics · Physics 2016-08-16 David Cubero , José Pablo Baltanás , Jesús Casado-Pascual

We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of…

Neurons and Cognition · Quantitative Biology 2012-12-07 Roni Vardi , Reut Timor , Shimon Marom , Moshe Abeles , Ido Kanter

We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses. On the…

Neurons and Cognition · Quantitative Biology 2015-11-20 Anastasia I. Lavrova , Michael A. Zaks , Lutz Schimansky-Geier

Complex spatiotemporal patterns, called chimera states, consist of coexisting coherent and incoherent domains and can be observed in networks of coupled oscillators. The interplay of synchrony and asynchrony in complex brain networks is an…

Adaptation and Self-Organizing Systems · Physics 2019-06-20 Teresa Chouzouris , Iryna Omelchenko , Anna Zakharova , Jaroslav Hlinka , Premysl Jiruska , Eckehard Schöll

We describe a new, computationally simple method for analyzing the dynamics of neuronal spike trains driven by external stimuli. The goal of our method is to test the predictions of simple spike-generating models against extracellularly…

Neurons and Cognition · Quantitative Biology 2007-05-23 Daniel S. Reich , Jonathan D. Victor , Bruce W. Knight

Many central neurons, and in particular certain brainstem aminergic neurons exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz. A large number of ion channel types contribute to such spiking so that accurate…

Neurons and Cognition · Quantitative Biology 2015-08-25 Henry C. Tuckwell , Ying Zhou , Nicholas J. Penington

Brain operates at remarkably low signal power. It has been noted that noise may play a constructive role in neural networks and facilitate the subthreshold signaling. The process of spiking pattern excitation at the characteristic neuronal…

Neurons and Cognition · Quantitative Biology 2024-08-12 Mariia Sorokina

Neural spike trains, which are sequences of very brief jumps in voltage across the cell membrane, were one of the motivating applications for the development of point process methodology. Early work required the assumption of stationarity,…

Applications · Statistics 2011-08-01 Robert E. Kass , Ryan C. Kelly , Wei-Liem Loh

We show that for two identical neuronal oscillators with strictly positive phase resetting curve, isochronous synchrony is an unstable attractor and arbitrarily weak noise can destroy entrainment and generate intermittent phase slips. Small…

Neurons and Cognition · Quantitative Biology 2016-11-18 Ehsan Bolhasani , Alireza Valizadeh

We provide rigorous and exact results characterizing the statistics of spike trains in a network of leaky integrate and fire neurons, where time is discrete and where neurons are submitted to noise, without restriction on the synaptic…

Dynamical Systems · Mathematics 2011-05-18 B. Cessac

Constructing electronic models of neurons has several applications including reproducing dynamics of biological neurons and their networks and neuroprosthetics. In the brain, most neurons themselves are in a non-oscillatory mode, and brain…

Adaptation and Self-Organizing Systems · Physics 2023-05-09 Nikita M. Egorov , Marina V. Sysoeva , Vladimir I. Ponomarenko , Ilya V. Sysoev

In this manuscript, a silent resonator neuron is coupled with a spiking integrator neuron through the gap junction, when the coupled neurons are of different types of excitability and none of the coupled neurons exhibit mixed mode…

Dynamical Systems · Mathematics 2024-01-18 Mohammad Reza Razvan , Somaye Yasaman

We analyze the response of the Hodgkin-Huxley neuron to a large number of uncorrelated stochastic inhibitory and excitatory post-synaptic spike trains. In order to clarify the various mechanisms responsible for noise-induced spike…

Disordered Systems and Neural Networks · Physics 2007-05-23 Alessandro Torcini , Stefano Luccioli , Thomas Kreuz

We address the questions of identifying pairs of interacting neurons from the observation of their spiking activity. The neuronal network is modeled by a system of interacting point processes with memory of variable length. The influence of…

Statistics Theory · Mathematics 2021-06-22 Emilio De Santis , Antonio Galves , Giovanna Nappo , Mauro Piccioni

The impact of inhibitory and excitatory synapses in delay-coupled Hodgkin--Huxley neurons that are driven by noise is studied. If both synaptic types are used for coupling, appropriately tuned delays in the inhibition feedback induce…

Neurons and Cognition · Quantitative Biology 2012-05-01 Qingyun Wang , Honghui Zhang , Matjaz Perc , Guanrong Chen

We study the stochastic FitzHugh-Nagumo equations, modelling the dynamics of neuronal action potentials, in parameter regimes characterised by mixed-mode oscillations. The interspike time interval is related to the random number of…

Probability · Mathematics 2012-07-10 Nils Berglund , Damien Landon

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

The stability of synchronous states is analysed in the context of two populations of inhibitory and excitatory neurons, characterized by different pulse-widths. The problem is reduced to that of determining the eigenvalues of a suitable…

Neurons and Cognition · Quantitative Biology 2020-02-04 Afifurrahman , Ekkehard Ullner , Antonio Politi

We study the stochastic dynamics of strongly-coupled excitable elements on a tree network. The peripheral nodes receive independent random inputs which may induce large spiking events propagating through the branches of the tree and leading…

Biological Physics · Physics 2017-07-14 Justus Kromer , Ali Khaledi-Nasab , Lutz Schimansky-Geier , Alexander B. Neiman

The Hodgkin-Huxley model describes action potential generation in certain types of neurons and is a standard model for conductance-based, excitable cells. Following the early work of Winfree and Best, this paper explores the response of a…

Dynamical Systems · Mathematics 2009-11-11 Kevin K. Lin
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