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Given the structure of a novel molecule, there is still no one who can reliably predict what odor percept that molecule will evoke. The challenge comes from both the difficulty in quantitatively characterizing molecular structure, and the…

Neurons and Cognition · Quantitative Biology 2018-06-08 Daniel Kepple , Alexei Koulakov

In this paper, we present the Monte-Carlo Compressive Optimization algorithm, a new method to solve a combinatorial optimization problem that is assumed compressible. The method relies on random queries to the objective function in order to…

Optimization and Control · Mathematics 2025-10-30 Baptiste Chevalier , Shimpei Yamaguchi , Wojciech Roga , Masahiro Takeoka

In order to understand the long known anomalies in the composition dependence of diffusion and viscosity of binary mixtures, we introduce here two new models and carry out extensive molecular dynamic simulations. In these models, the two…

Statistical Mechanics · Physics 2009-10-31 Arnab Mukherjee , Goundla Srinivas , Biman Bagchi

Angular is one of the most widely adopted frameworks for developing large-scale, dynamic web applications. As projects increase in scope and complexity, developers face growing challenges in managing architecture and maintaining clean,…

Software Engineering · Computer Science 2026-05-01 Maykon Nunes , Emanuel Coutinho , Carla Bezerra , Ivan Machado

Offline handwriting recognition (HWR) has improved significantly with the advent of deep learning architectures in recent years. Nevertheless, it remains a challenging problem and practical applications often rely on post-processing…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Andrey Totev , Tomas Ward

Use copula to model dependency of variable extends multivariate gaussian assumption. In this paper we first empirically studied copula regression model with continous response. Both simulation study and real data study are given. Secondly…

Methodology · Statistics 2021-01-05 Weijian Luo , Mai Wo

A simple phenomenological model of a binary granular mixture is developed and investigated numerically. We attempt to model the experimental system of [1,2] where a horizontally vibrated binary monolayer was found to exhibit a transition…

Statistical Mechanics · Physics 2009-11-10 George C. M. A. Ehrhardt , Andrew Stephenson , Pedro M. Reis

During the past few years the development of experimental techniques has allowed the quantitative analysis of biological systems ranging from neurobiology and molecular biology. This work focuses on the quantitative description of these…

Biomolecules · Quantitative Biology 2011-09-19 Carlo Barbieri

Predicting the thermodynamic properties of mixtures is crucial for process design and optimization in chemical engineering. Machine learning (ML) methods are gaining increasing attention in this field, but experimental data for training are…

Machine Learning · Computer Science 2024-10-10 Dominik Gond , Jan-Tobias Sohns , Heike Leitte , Hans Hasse , Fabian Jirasek

Reaction-times in perceptual tasks are the subject of many experimental and theoretical studies. With the neural decision making process as main focus, most of these works concern discrete (typically binary) choice tasks, implying the…

Neurons and Cognition · Quantitative Biology 2012-03-01 Laurent Bonnasse-Gahot , Jean-Pierre Nadal

In this paper we propose the use of the Word2vec algorithm in order to obtain odor perception embeddings (or smell embeddings), only using publicly available perfume descriptions. Besides showing meaningful similarity relationships among…

Computation and Language · Computer Science 2022-03-22 Janek Amann , Manex Agirrezabal

Insects identify and evaluate behaviorally relevant odorants in complex natural scenes where odor concentrations and mixture composition can change rapidly. In the honeybee, a combinatorial code of activated and inactivated projection…

Biological Physics · Physics 2011-01-06 Martin Paul Nawrot , Sabine Krofczik , Farzad Farkhooi , Randolf Menzel

Collective cell migration in response to a chemical cue occurs in many biological processes such as morphogenesis and cancer metastasis. Clusters of migratory cells in these systems are capable of responding to gradients of less than 1%…

Biological Physics · Physics 2016-08-24 Julien Varennes , Bumsoo Han , Andrew Mugler

Adaptive response to a varying environment is a common feature of biological organisms. Reproducing such features in electronic systems and circuits is of great importance for a variety of applications. Here, we consider memory models…

Cell Behavior · Quantitative Biology 2013-10-29 Fabio Lorenzo Traversa , Yuriy V. Pershin , Massimiliano Di Ventra

Code Smell, similar to a bad smell, is a surface indication of something tainted but in terms of software writing practices. This metric is an indication of a deeper problem lies within the code and is associated with an issue which is…

Software Engineering · Computer Science 2021-08-11 Himanshu Gupta , Tanmay G. Kulkarni , Lov Kumar , Lalita Bhanu Murthy Neti , Aneesh Krishna

Code smells are indicators of potential design flaws in source code and do not appear alone but in combination with other smells, creating complex interactions. While existing literature classifies these smell interactions into collocated,…

Software Engineering · Computer Science 2025-04-28 Ruchin Gupta , Sandeep Kumar Singh

In this paper, we propose a general framework for combining evidence of varying quality to estimate underlying binary latent variables in the presence of restrictions imposed to respect the scientific context. The resulting algorithms…

Methodology · Statistics 2018-08-28 Zhenke Wu , Livia Casciola-Rosen , Antony Rosen , Scott L. Zeger

A recent paper in a prominent science magazine claims to show that humans can discriminate at least 1 trillion odors. The authors reached that conclusion after performing just 260 comparisons of two smells, of which about half could be…

Neurons and Cognition · Quantitative Biology 2016-09-09 Markus Meister

Out-of-distribution (OOD) detection identifies test samples that differ from the training data, which is critical to ensuring the safety and reliability of machine learning (ML) systems. While a plethora of methods have been developed to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Viet Duong , Qiong Wu , Zhengyi Zhou , Eric Zavesky , Jiahe Chen , Xiangzhou Liu , Wen-Ling Hsu , Huajie Shao

A regression model is proposed for the analysis of an ordinal response variable depending on a set of multiple covariates containing ordinal and potentially other variables. The proportional odds model (McCullagh (1980)) is used for the…

Methodology · Statistics 2018-04-25 Javier Espinosa , Christian Hennig
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