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We review a recent trend in computational systems biology which aims at using pattern recognition algorithms to infer the structure of large-scale biological networks from heterogeneous genomic data. We present several strategies that have…

Quantitative Methods · Quantitative Biology 2008-09-22 Jean-Philippe Vert

Complex networks are universal, arising in fields as disparate as sociology, physics, and biology. In the past decade, extensive research into the properties and behaviors of complex systems has uncovered surprising commonalities among the…

Other Quantitative Biology · Quantitative Biology 2015-06-26 Claire Christensen , Reka Albert

Networks are widely used in the biological, physical, and social sciences as a concise mathematical representation of the topology of systems of interacting components. Understanding the structure of these networks is one of the outstanding…

Data Analysis, Statistics and Probability · Physics 2007-06-21 M. E. J. Newman , E. A. Leicht

This article discusses how concepts and methods of complex networks can be applied to real-time imaging and computer vision. After a brief introduction of complex networks basic concepts, their use as means to represent and characterize…

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Luciano da Fontoura Costa

Complex network theory has been applied to solving practical problems from different domains. In this paper, we present a general framework for complex network applications. The keys of a successful application are a thorough understanding…

Physics and Society · Physics 2015-07-22 Xiao Fan Liu , Chi Kong Tse

Over the past decade network theory has turned out to be a powerful methodology to investigate complex systems of various sorts. Through data analysis, modeling, and simulation quite an unparalleled insight into their structure, function,…

Physics and Society · Physics 2010-07-16 Kimmo Kaski

Complex networks are an important paradigm of modern complex systems sciences which allows quantitatively assessing the structural properties of systems composed of different interacting entities. During the last years, intensive efforts…

Complex networks pervade various real-world systems, from the natural environment to human societies. The essence of these networks is in their ability to transition and evolve from microscopic disorder-where network topology and node…

Social and Information Networks · Computer Science 2025-06-10 Jingtao Ding , Chang Liu , Yu Zheng , Yunke Zhang , Zihan Yu , Ruikun Li , Hongyi Chen , Jinghua Piao , Huandong Wang , Jiazhen Liu , Yong Li

In network science complex systems are represented as a mathematical graphs consisting of a set of nodes representing the components and a set of edges representing their interactions. The framework of networks has led to significant…

Physics and Society · Physics 2022-04-07 Alexandre Bovet , Hernán A. Makse

These are exciting times for quantum physics as new quantum technologies are expected to soon transform computing at an unprecedented level. Simultaneously network science is flourishing proving an ideal mathematical and computational…

Quantum Physics · Physics 2024-06-13 Johannes Nokkala , Jyrki Piilo , Ginestra Bianconi

Complex systems are characterized by many interacting units that give rise to emergent behavior. A particularly advantageous way to study these systems is through the analysis of the networks that encode the interactions among the system's…

Physics and Society · Physics 2019-03-21 Alberto Aleta , Yamir Moreno

In this paper, we present a survey of the use of graph theoretical techniques in Biology. In particular, we discuss recent work on identifying and modelling the structure of bio-molecular networks, as well as the application of centrality…

Molecular Networks · Quantitative Biology 2007-05-23 Oliver Mason , Mark Verwoerd

The response of complex networks to perturbations is of utmost importance in areas as diverse as ecosystem management, emergency response, and cell reprogramming. A fundamental property of networks is that the perturbation of one node can…

Molecular Networks · Quantitative Biology 2011-05-20 Sean P. Cornelius , William L. Kath , Adilson E. Motter

The increasing interest in complex networks research has been a consequence of several intrinsic features of this area, such as the generality of the approach to represent and model virtually any discrete system, and the incorporation of…

A cell's behavior is a consequence of the complex interactions between its numerous constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling pathways and regulatory mechanisms to coordinate multiple processes,…

Molecular Networks · Quantitative Biology 2007-09-12 Reka Albert

Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient control of metabolic fluxes remains elusive for large-scale…

Molecular Networks · Quantitative Biology 2015-09-04 Georg Basler , Zoran Nikoloski , Abdelhalim Larhlimi , Albert-László Barabási , Yang-Yu Liu

The rapidly developing theory of complex networks indicates that real networks are not random, but have a highly robust large-scale architecture, governed by strict organizational principles. Here, we focus on the properties of biological…

Molecular Networks · Quantitative Biology 2007-05-23 E. Almaas , A. -L. Barabasi

What do societies, the Internet, and the human brain have in common? They are all examples of complex relational systems, whose emerging behaviours are largely determined by the non-trivial networks of interactions among their constituents,…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Vito Latora

Biomolecular networks have already found great utility in characterizing complex biological systems arising from pair-wise interactions amongst biomolecules. Here, we review how graph theoretical approaches can be applied not only for a…

Molecular Networks · Quantitative Biology 2018-12-03 Heeralal Janwa , Steven E. Massey , Julian Velev , Bud Mishra

Modern communication networks are inherently complex in nature. First of all, they have a large number of heterogeneous components. Secondly, their connectivity is extremely dynamic. Nodes can come and go, links can be removed and added…

Social and Information Networks · Computer Science 2017-08-08 Bisma S. Khan , Muaz A. Niazi