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We study the evolution of a population in a two-locus genotype space, in which the negative effects of two single mutations are overcompensated in a high fitness double mutant. We discuss how the interplay of finite population size, $N$,…

Populations and Evolution · Quantitative Biology 2011-02-23 Alexander Altland , Andrej Fischer , Joachim Krug , Ivan G. Szendro

More and more evidence shows that mating preference is a mechanism that may lead to a reproductive isolation event. In this paper, a haploid population living on two patches linked by migration is considered. Individuals are ecologically…

Populations and Evolution · Quantitative Biology 2018-05-08 Helene Leman

We present a model for biological aging that considers the number of individuals whose (inherited) genetic charge determines the maximum age for death: each individual may die before that age due to some external factor, but never after…

adap-org · Physics 2008-02-03 R. M. C. de Almeida , S. Moss de Oliveira , T. J. P. Penna

Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of sex and recombination, the widespread pattern of…

Populations and Evolution · Quantitative Biology 2011-12-12 Yaniv Brandvain , Graham Coop

When the initial state of a quantum mechanical system is an excited state, then it is expected that the occupation, or survival, probability of that state will decrease. This is studied numerically within the Bixon-Jortner model, which was…

Quantum Physics · Physics 2023-09-08 James P. Lavine

The sexual version of the Penna model of biological ageing, simulated since 1996, is compared here with alternative forms of reproduction as well as with models not involving ageing. In particular we want to check how sexual forms of life…

Statistical Mechanics · Physics 2007-05-23 D. Stauffer , P. M. C. de Oliveira , S. Moss de Oliveira , T. J. P. Penna , J. S. Sa' Martins

The population in the sexual Penna ageing model is first separated into several reproductively isolated groups. Then, after equilibration, sexual mixing between the groups is allowed. We study the changes in the population size due to this…

Populations and Evolution · Quantitative Biology 2009-11-13 K. Bonkowska , M. Kula , S. Cebrat , D. Stauffer

We consider a stochastic model for a pathogen population in the presence of an immune response, in which pathogen types are partially ordered by ancestry and the immune system must eliminate ancestor types before it can eliminate their…

Probability · Mathematics 2026-02-03 Carolina Grejo , Fabio Lopes , Fábio Machado , Alejandro Roldán-Correa

Gene duplications are one of major primary driving forces for evolutionary novelty. We took population genetics models of genes duplicate to study how evolutionary forces acting during the fixation of mutant allele at duplicate loci. We…

Populations and Evolution · Quantitative Biology 2012-03-19 Yupeng Cun

In this paper we analyse the genetic evolution of a diploid hermaphroditic population, which is modelled by a three-type nonlinear birth-and-death process with competition and Mendelian reproduction. In a recent paper, Collet et al., 2013…

Probability · Mathematics 2017-08-28 Anton Bovier , Rebecca Neukirch

Predicting evolution of expanding populations is critical to control biological threats such as invasive species and cancer metastasis. Expansion is primarily driven by reproduction and dispersal, but nature abounds with examples of…

Populations and Evolution · Quantitative Biology 2019-04-26 Maxime Deforet , Carlos Carmona-Fontaine , Kirill S. Korolev , Joao B. Xavier

We analyze evolutionary dynamics in a confluent, branching cellular population, such as in a growing duct, vasculature, or in a branching microbial colony. We focus on the coarse-grained features of the evolution and build a statistical…

Populations and Evolution · Quantitative Biology 2022-02-15 Adam S. Bryant , Maxim O. Lavrentovich

We investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite, there may be infinitely many loci, and there are weak…

Populations and Evolution · Quantitative Biology 2011-09-20 Steven N. Evans , David Steinsaltz , Kenneth W. Wachter

A mathematical model of interacting species filling ecological niches left by the extinction of others is introduced. Species organize themselves into genera of all sizes. The size of a genus on average grows linearly with its age,…

Condensed Matter · Physics 2008-02-03 Susanna Manrubia , Maya Paczuski

Multitype branching processes are ideal for studying the population dynamics of stem cell populations undergoing mutation accumulation over the years following transplant. In such stochastic models, several quantities are of clinical…

Populations and Evolution · Quantitative Biology 2021-11-17 Timothy C Stutz , Janet S. Sinsheimer , Mary Sehl , Jason Xu

Population genetics struggles to model extinction; standard models track the relative rather than absolute fitness of genotypes, while the exceptions describe only the short-term transition from imminent doom to evolutionary rescue. But…

Populations and Evolution · Quantitative Biology 2017-02-20 Jason Bertram , Kevin Gomez , Joanna Masel

When beneficial mutations are relatively common, competition between multiple unfixed mutations can reduce the rate of fixation in well-mixed asexual populations. We introduce a one dimensional model with a steady accumulation of beneficial…

Populations and Evolution · Quantitative Biology 2013-02-19 Jakub Otwinowski , Stefan Boettcher

We study the dynamics of an age-structured population in which the life expectancy of an offspring may be mutated with respect to that of its parent. When advantageous mutation is favored, the average fitness of the population grows…

Statistical Mechanics · Physics 2009-10-31 W. Hwang , P. L. Krapivsky , S. Redner

In evolutionary algorithms, the fitness of a population increases with time by mutating and recombining individuals and by a biased selection of more fit individuals. The right selection pressure is critical in ensuring sufficient…

Artificial Intelligence · Computer Science 2007-05-23 Marcus Hutter

Sexual reproduction presents significant challenges to formal treatment of evolutionary processes. A starting point for systematic treatments of ecological and evolutionary phenomena has been provided by the gene centered view of evolution…

Biological Physics · Physics 2009-11-06 Hiroki Sayama , Les Kaufman , Yaneer Bar-Yam