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Motivation: Clustering techniques are routinely applied to identify patterns of co-expression in gene expression data. Co-regulation, and involvement of genes in similar cellular function, is subsequently inferred from the clusters which…

Quantitative Methods · Quantitative Biology 2016-06-10 Patrick E. McSharry , Edmund J. Crampin

We develop sampling algorithms to fit Bayesian hierarchical models, the computational complexity of which scales linearly with the number of observations and the number of parameters in the model. We focus on crossed random effect and…

Computation · Statistics 2025-01-03 Omiros Papaspiliopoulos , Timothée Stumpf-Fétizon , Giacomo Zanella

One basic requirement of many studies is the necessity of classifying data. Clustering is a proposed method for summarizing networks. Clustering methods can be divided into two categories named model-based approaches and algorithmic…

Machine Learning · Computer Science 2013-02-19 Raheleh Namayandeh , Farzad Didehvar , Zahra Shojaei

Microarray data analysis is one of the major area of research in the field computational biology. Numerous techniques like clustering, biclustering are often applied to microarray data to extract meaningful outcomes which play key roles in…

Neural and Evolutionary Computing · Computer Science 2019-09-04 Shubhankar Mohapatra , Moumita Sarkar , Anjali Mohapatra , Bhawani Sankar Biswal

The explosion in the amount of data available for analysis often necessitates a transition from batch to incremental clustering methods, which process one element at a time and typically store only a small subset of the data. In this paper,…

Machine Learning · Computer Science 2014-06-26 Margareta Ackerman , Sanjoy Dasgupta

In several environmental applications data are functions of time, essentially con- tinuous, observed and recorded discretely, and spatially correlated. Most of the methods for analyzing such data are extensions of spatial statistical tools…

Methodology · Statistics 2011-06-28 Elvira Romano , Antonio Balzanella , Rosanna Verde

We study supervised learning problems using clustering constraints to impose structure on either features or samples, seeking to help both prediction and interpretation. The problem of clustering features arises naturally in text…

Machine Learning · Computer Science 2016-09-20 Vincent Roulet , Fajwel Fogel , Alexandre d'Aspremont , Francis Bach

Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide…

Methodology · Statistics 2023-03-02 Paul D. W. Kirk , Filippo Pagani , Sylvia Richardson

Quality assessments of models in unsupervised learning and clustering verification in particular have been a long-standing problem in the machine learning research. The lack of robust and universally applicable cluster validity scores often…

Machine Learning · Statistics 2018-03-30 Luzie Helfmann , Johannes von Lindheim , Mattes Mollenhauer , Ralf Banisch

We present a new algorithm for clustering longitudinal data. Data of this type can be conceptualized as consisting of individuals and, for each such individual, observations of a time-dependent variable made at various times. Generically,…

Machine Learning · Computer Science 2026-03-17 Marie-Pierre Sylvestre , Laurence Boulanger

The area of constrained clustering has been extensively explored by researchers and used by practitioners. Constrained clustering formulations exist for popular algorithms such as k-means, mixture models, and spectral clustering but have…

Machine Learning · Computer Science 2021-01-11 Hongjing Zhang , Tianyang Zhan , Sugato Basu , Ian Davidson

We herein introduce a new method of interpretable clustering that uses unsupervised binary trees. It is a three-stage procedure, the first stage of which entails a series of recursive binary splits to reduce the heterogeneity of the data…

Methodology · Statistics 2023-12-29 Ricardo Fraiman , Badih Ghattas , Marcela Svarc

Causal inference analyses often use existing observational data, which in many cases has some clustering of individuals. In this paper we discuss propensity score weighting methods in a multilevel setting where within clusters individuals…

Applications · Statistics 2020-12-24 Youjin Lee , Trang Q. Nguyen , Elizabeth A. Stuart

Both cluster randomized trials and quasi-experimental designs are used to evaluate the impact of health and social policies and interventions. Stepped-wedge cluster randomized trials randomize a staggered adoption approach, while recent…

Methodology · Statistics 2026-04-15 Haidong Lu , Gregg S. Gonsalves , Fan Li , Guanyu Tong , Lee Kennedy-Shaffer

In this paper we develop a method for clustering belief functions based on attracting and conflicting metalevel evidence. Such clustering is done when the belief functions concern multiple events, and all belief functions are mixed up. The…

Artificial Intelligence · Computer Science 2007-05-23 Johan Schubert

A model based clustering procedure for data of mixed type, clustMD, is developed using a latent variable model. It is proposed that a latent variable, following a mixture of Gaussian distributions, generates the observed data of mixed type.…

Methodology · Statistics 2015-11-06 Damien McParland , Isobel Claire Gormley

Traditional clustering methods aim to group unlabeled data points based on their similarity to each other. However, clustering, in the absence of additional information, is an ill-posed problem as there may be many different, yet equally…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Bingchen Zhao , Oisin Mac Aodha

In this work, we study the problem of clustering survival data $-$ a challenging and so far under-explored task. We introduce a novel semi-supervised probabilistic approach to cluster survival data by leveraging recent advances in…

We present a system for summarization and interactive exploration of high-valued aggregate query answers to make a large set of possible answers more informative to the user. Our system outputs a set of clusters on the high-valued query…

Databases · Computer Science 2018-08-01 Yuhao Wen , Xiaodan Zhu , Sudeepa Roy , Jun Yang

There is increasing interest in combining information from experimental studies, including randomized and single-group trials, with information from external experimental or observational data sources. Such efforts are usually motivated by…

Methodology · Statistics 2026-04-23 Lawson Ung , Guanbo Wang , Sebastien Haneuse , Miguel A. Hernán , Issa J. Dahabreh
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