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We consider a reaction-diffusion model for a population structured in phenotype. We assume that the population lives in a heterogeneous periodic environment, so that a given phenotypic trait may be more or less fit according to the spatial…

Analysis of PDEs · Mathematics 2025-03-07 Nathanaël Boutillon , Luca Rossi

Resistance to insecticide is considered nowadays one of the major threats to insect control, as its occurrence reduces drastically the efficiency of chemical control campaigns, and may also perturb the application of other control methods,…

Optimization and Control · Mathematics 2019-12-24 Pastor E. Pérez-Estigarribia , Pierre-Alexandre Bliman , Christian Schaerer

A microscopic approach to macroeconomic features is intended. A model for macroeconomic behavior under heterogeneous spatial economic conditions is reviewed. A birth-death lattice gas model taking into account the influence of an economic…

Statistical Mechanics · Physics 2009-11-10 Marcel Ausloos , Paulette Clippe , Janusz Miśkiewicz , Andrzej Pekalski

Models of population growth and extinction are an increasingly popular subject of study. However, consequences of stochasticity and noise in shaping distributions and outcomes are not sufficiently explored. Here we consider a distributed…

Statistical Mechanics · Physics 2020-11-11 Bertrand Ottino-Löffler , Mehran Kardar

We have simulated the evolution of age structured populations whose individuals represented by their diploid genomes were distributed on a square lattice. The environmental conditions on the whole territory changed simultaneously in the…

Populations and Evolution · Quantitative Biology 2009-11-05 Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the…

Populations and Evolution · Quantitative Biology 2012-08-01 Richard A. Neher , Thomas Leitner

Mutation rate is a key determinant of the pace as well as outcome of evolution, and variability in this rate has been shown in different scenarios to play a key role in evolutionary adaptation and resistance evolution under stress caused by…

Populations and Evolution · Quantitative Biology 2019-03-01 Dalit Engelhardt , Eugene I. Shakhnovich

Exploiting the mathematical curiosity of intransitive dice, we present a simple theoretical model for co-evolution that captures scales ranging from the genome of the individual to the system-wide emergence of species diversity. We study a…

Populations and Evolution · Quantitative Biology 2022-12-02 Julius B. Kirkegaard , Kim Sneppen

Adaptation is a central topic in theoretical biology, of practical importance for analyzing drug resistance mutations. Several authors have used arguments based on extreme value theory in their work on adaptation. There are complications…

Populations and Evolution · Quantitative Biology 2013-12-17 Kristina Crona , Devin Greene , Miriam Barlow

We discuss the effects of movement and spatial heterogeneity on population dynamics via reaction-diffusion-advection models, focusing on the persistence, competition, and evolution of organisms in spatially heterogeneous environments.…

Analysis of PDEs · Mathematics 2020-07-08 King-Yeung Lam , Shuang Liu , Yuan Lou

Random walks on multidimensional nonlinear landscapes are of interest in many areas of science and engineering. In particular, properties of adaptive trajectories on fitness landscapes determine population fates and thus play a central role…

Populations and Evolution · Quantitative Biology 2014-10-08 Michael Manhart , Alexandre V. Morozov

The adaptation rate in theoretical models of biological evolution increases with the mutation rate but only to a point when mutations into lethal states cause extinction. One would expect that removing such states should be beneficial for…

Populations and Evolution · Quantitative Biology 2024-06-27 Viktoria Blavatska , Bartlomiej Waclaw

Evolutionary dynamics can be studied in well-mixed or structured populations. Population structure typically arises from the heterogeneous distribution of individuals in physical space or on social networks. Here we introduce a new type of…

Populations and Evolution · Quantitative Biology 2009-06-04 Tibor Antal , Hisashi Ohtsuki , John Wakeley , Peter D. Taylor , Martin A. Nowak

We consider a trait-structured population subject to mutation, birth and competition of logistic type, where the number of coexisting types may fluctuate. Applying a limit of rare mutations to this population while keeping the population…

Probability · Mathematics 2011-12-05 Nicolas Champagnat , Amaury Lambert

We propose a model to characterize how a diffusing population adapts under a time periodic selection, while its environment undergoes shifts and size changes, leading to significant differences with classical results on fixed domains. After…

Analysis of PDEs · Mathematics 2025-06-05 Matthieu Alfaro , Adel Blouza , Nessim Dhaouadi

We study the extinction risk of a fragmented population residing on a network of patches coupled by migration, where the local patch dynamics include the Allee effect. We show that mixing between patches dramatically influences the…

Populations and Evolution · Quantitative Biology 2020-02-05 Ohad Vilk , Michael Assaf

Owing to the analogies between the problem of wealth redistribution with taxation in a multi-agent society, we introduce and discuss a kinetic model describing the statistical distributions in time of the sizes of groups of biological…

Populations and Evolution · Quantitative Biology 2023-11-15 Giuseppe Toscani , Mattia Zanella

Darwinian evolution can be modeled in general terms as a flow in the space of fitness (i.e. reproductive rate) distributions. In the diffusion approximation, Tsimring et al. have showed that this flow admits "fitness wave" solutions:…

Populations and Evolution · Quantitative Biology 2017-01-30 Matteo Smerlak , Ahmed Youssef

The question of whether biological populations survive or are eventually driven to extinction has long been examined using mathematical models. In this work we study population survival or extinction using a stochastic, discrete…

Populations and Evolution · Quantitative Biology 2021-09-15 Yifei Li , Stuart T. Johnston , Pascal R. Buenzli , Peter van Heijster , Matthew J. Simpson

Habitat loss, driven primarily by anthropogenic activity, significantly threatens ecosystem sustainability. While it is well understood that habitat loss is the leading contributor to declines in biodiversity worldwide, the connection…

Analysis of PDEs · Mathematics 2024-10-10 Yurij Salmaniw , Zhongwei Shen , Hao Wang