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Related papers: Dynamic Pathways for Viral Capsid Assembly

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Active nematics are out-of-equilibrium systems in which energy injection at the microscale drives emergent collective behaviors, from spontaneous flows to active turbulence. While the dynamics of these systems have been extensively studied,…

Soft Condensed Matter · Physics 2025-04-15 Ahmet Umut Akduman , Yusuf Sariyar , Giuseppe Negro , Livio Nicola Carenza

The kinetics for the assembly of viral proteins into a population of capsids can be measured in vitro with size exclusion chromatography or dynamic light scattering, but extracting mechanistic information from these studies is challenging.…

Biomolecules · Quantitative Biology 2015-05-13 Michael F. Hagan

We consider the self-assembly of composite structures from a group of nanocomponents, each consisting of particles within an $N$-atom system. Self-assembly pathways and rates for nanocomposites are derived via a multiscale analysis of the…

Biological Physics · Physics 2014-01-06 Stephen Pankavich , Peter Ortoleva

In the self-assembly process which drives the formation of cellular membranes, micelles, and capsids, a collection of separated subunits spontaneously binds together to form functional and more ordered structures. In this work, we study the…

Biological Physics · Physics 2021-05-04 Mobolaji Williams

We describe collective-move Monte Carlo algorithms designed to approximate the overdamped dynamics of self-assembling nanoscale components equipped with strong, short-ranged and anisotropic interactions. Conventional Monte Carlo simulations…

Statistical Mechanics · Physics 2012-04-16 Stephen Whitelam

Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse…

Biomolecules · Quantitative Biology 2010-06-08 Stefan Auer , Antonio Trovato , Michele Vendruscolo

Self-organized complex structures in nature, e.g. viral capsids, hierarchical biopolymers, and bacterial flagella, offer efficiency, adaptability, robustness, and multi-functionality. Can we program the self-assembly of three-dimensional…

Soft Condensed Matter · Physics 2022-01-11 Francesco Serafin , Jun Lu , Nicholas Kotov , Kai Sun , Xiaoming Mao

Inertial particles advected in chaotic flows often accumulate in strange attractors. While moving in these fractal sets they usually approach each other and collide. Here we consider inertial particles aggregating upon collision. The new…

Fluid Dynamics · Physics 2009-11-13 Jens C. Zahnow , Rafael D. Vilela , Ulrike Feudel , Tamas Tel

We use neuroevolutionary learning to identify time-dependent protocols for low-dissipation self-assembly in a model of generic active particles with interactions. When the time allotted for assembly is sufficiently long, low-dissipation…

Statistical Mechanics · Physics 2022-09-19 Stephen Whitelam , Jeremy D. Schmit

The protein shells, or capsids, of all sphere-like viruses adopt icosahedral symmetry. In the present paper we propose a statistical thermodynamic model for viral self-assembly. We find that icosahedral symmetry is not expected for viral…

Soft Condensed Matter · Physics 2009-11-07 Robijn F. Bruinsma , William M. Gelbart , David Reguera , Joseph Rudnick , Roya Zandi

We propose a description for the quasi-equilibrium self-assembly of small, single-stranded (ss) RNA viruses whose capsid proteins (CPs) have flexible, positively charged, disordered tails that associate with the negatively charged RNA…

Soft Condensed Matter · Physics 2016-03-23 Robijn F. Bruinsma , Mauricio Comas-Garcia , Rees F. Garmann , Alexander Y. Grosberg

We examine the budding of a nanoscale particle through a lipid bilayer using molecular dynamics simulations, free energy calculations, and an elastic theory, with the aim of determining the extent to which equilibrium elasticity theory can…

Subcellular Processes · Quantitative Biology 2012-02-22 Teresa Ruiz-Herrero , Enrique Velasco , Michael F. Hagan

We characterize the self-assembly of colloidal particles with surface mobile DNA linkers under kinetically limited valence conditions. For this, we put forward a computer simulation model that captures quantitatively the interplay between…

Soft Condensed Matter · Physics 2022-10-26 Pedro A. Sánchez , Alessio Caciagli , Sofia S. Kantorovich , Erika Eiser

For problems in astrophysics, planetary science and beyond, numerical simulations are often limited to simulating fewer particles than in the real system. To model collisions, the simulated particles (aka superparticles) need to be inflated…

Earth and Planetary Astrophysics · Physics 2020-06-03 David Nesvorny , Andrew N. Youdin , Raphael Marschall , Derek C. Richardson

Complex colloidal cluster morphologies are desirable for the fabrication of advanced materials, such as photonic crystals and meta-materials, and can be formed through evaporation-driven packing. By coupling lattice Boltzmann and discrete…

Soft Condensed Matter · Physics 2026-05-07 Junyu Yang , Abhinav Naga , Xitong Zhang , Halim Kusumaatmaja

Image-guided object assembly represents a burgeoning research topic in computer vision. This paper introduces a novel task: translating multi-view images of a structural 3D model (for example, one constructed with building blocks drawn from…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hongyu Yan , Yadong Mu

Single-stranded (ss) RNA viruses self-assemble spontaneously in solutions that contain the viral RNA genome molecules and the viral capsid proteins. The self-assembly of empty capsids can be understood on the basis of free energy…

Biological Physics · Physics 2021-08-21 Inbal Mizrahi , Robijn Bruinsma , Joseph Rudnick

A major goal in nanoscience and nanotechnology is the self-assembly of any desired complex structure with a system of particles interacting through simple potentials. To achieve this objective, intense experimental and theoretical efforts…

Soft Condensed Matter · Physics 2014-09-11 Daniel Salgado-Blanco , Carlos I. Mendoza

We use numerical simulations to show how noninteracting hard particles binding to a deformable elastic shell may self-assemble into a variety of linear patterns. This is a result of the nontrivial elastic response to deformations of shells.…

Soft Condensed Matter · Physics 2011-02-25 Andela Šarić , Angelo Cacciuto

This article proposes a new way to construct computationally efficient `wrappers' around fine scale, microscopic, detailed descriptions of dynamical systems, such as molecular dynamics, to make predictions at the macroscale `continuum'…

Dynamical Systems · Mathematics 2017-03-06 Hammad Alotaibi , Barry Cox , A. J. Roberts