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The full understanding of cellular functions requires information about protein numbers for various biomolecular assemblies and their dynamics, which can be partly accessed by super-resolution fluorescence microscopy. Yet, many protein…

Biological Physics · Physics 2020-06-17 Kristin S. Grußmayer , Klaus Yserentant , Dirk-Peter Herten

A path integral formulation is developed to study the spectrum of radiation from a perfectly reflecting (conducting) surface. It allows us to study arbitrary deformations in space and time. The spectrum is calculated to second order in the…

Quantum Physics · Physics 2009-10-31 Faez Miri , Ramin Golestanian

Raman spectroscopy is widely used across scientific domains to characterize the chemical composition of samples in a non-destructive, label-free manner. Many applications entail the unmixing of signals from mixtures of molecular species to…

Magnetic resonance imaging (MRI) is the method of choice for noninvasive studies of micrometer-scale structures in biological tissues via their effects on the time/frequency-dependent ("restricted") and anisotropic self-diffusion of water.…

Soft Condensed Matter · Physics 2021-11-16 Omar Narvaez , Maxime Yon , Hong Jiang , Diana Bernin , Eva Forssell-Aronsson , Alejandra Sierra , Daniel Topgaard

Wavefront-shaping is a promising approach for imaging fluorescent targets deep inside scattering tissue despite strong aberrations. It enables focusing an incoming illumination into a single spot inside tissue, as well as correcting the…

Optics · Physics 2024-01-23 Dror Aizik , Anat Levin

We present a numerical method for calculating piecewise smooth spectral functions of correlated quantum systems in the thermodynamic limit from the spectra of finite systems computed using the dynamical or correction-vector density-matrix…

Strongly Correlated Electrons · Physics 2014-05-05 Martin Paech , Eric Jeckelmann

Fluorescence molecular tomography (FMT) is a sensitive optical imaging technology widely used in biomedical research. However, the ill-posedness of the inverse problem poses a huge challenge to FMT reconstruction. Although end-to-end deep…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Peng Zhang , Qianqian Xue , Xingyu Liu , Guanglei Zhang , Wenjian Wang , Jiye Liang

In Minimally Invasive Surgery (MIS), tissue scanning with imaging probes is required for subsurface visualisation to characterise the state of the tissue. However, scanning of large tissue surfaces in the presence of deformation is a…

Robotics · Computer Science 2021-01-12 Jian Zhan , Joao Cartucho , Stamatia Giannarou

The development of molecular diagnostic tools to achieve individualized medicine requires identifying predictive biomarkers associated with subgroups of individuals who might receive beneficial or harmful effects from different available…

Methodology · Statistics 2020-01-20 Shonosuke Sugasawa , Hisashi Noma

We present a formula to evaluate the spontaneous emission spectra of an atom in contact with a radiation field with non-Markovian effects. This formula is written in terms of a two-time correlation of system observables and the…

Quantum Physics · Physics 2017-08-17 Ines de Vega , Daniel Alonso

We propose a method to reconstruct the density of a luminescent source in a highly-scattering medium from ultrasound modulated optical measurements. Our approach is based on the solution to a hybrid inverse source problem for the diffusion…

Optics · Physics 2015-06-17 Guillaume Bal , John C Schotland

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

Wavefront shaping correction makes it possible to image fluorescent particles deep inside scattering tissue. This requires determining a correction mask to be placed in both excitation and emission paths. Standard approaches select…

Optics · Physics 2022-06-22 Dror Aizik , Ioannis Gkioulekas , Anat Levin

Single molecule fluorescence microscopy is a powerful technique for uncovering detailed information about biological systems, both in vitro and in vivo. In such experiments, the inherently low signal to noise ratios mean that accurate…

Computer Vision and Pattern Recognition · Computer Science 2013-06-10 Ji Won Yoon

To overcome the physical barriers caused by light diffraction, super-resolution techniques are often applied in fluorescence microscopy. State-of-the-art approaches require specific and often demanding acquisition conditions to achieve…

Spectrum denoising is an important procedure for large-scale spectroscopical surveys. This work proposes a novel stellar spectrum denoising method based on deep Bayesian modeling. The construction of our model includes a prior distribution…

Instrumentation and Methods for Astrophysics · Physics 2021-09-08 Xin Kang , Shiyuan He , Yanxia Zhang

We present a method of creation of photonic structures whose optical spectrum of the reflection coefficient has an arbitrary shape and has predetermined features. We develop an algorithm for the construction of a photonic crystal structure,…

Optics · Physics 2023-05-16 S. E. Svyakhovskiy , N. I. Pyshkov

We describe an interferometer based on fluorescent emission of radiation of two qubits in quasi-one-dimensional modes. Such a system can be readily realized with dipole emitters near conducting surface-plasmonic nanowires or with…

Quantum Physics · Physics 2010-10-04 G. S. Paraoanu

We report on a Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - Infra - Red (FTIR) spectrometer. In contrast to the conventional surface plasmon technique, operating at a fixed wavelength and a variable angle of…

Soft Condensed Matter · Physics 2013-03-19 V. Lirtsman , M. Golosovsky , D. Davidov

We present an approach for the description of fluorescence from optically active material embedded in layered periodic structures. Based on an exact electromagnetic Green's tensor analysis, we determine the radiative properties of emitters…

Mesoscale and Nanoscale Physics · Physics 2015-10-20 Francesco Intravaia , Kurt Busch
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